Testing Data
(Gel: 10%SDS-PAGE Lysates (from left to right): Rat kidney tissue Amount of lysate: 40ug per lane Primary antibody: 1/350 dilution Secondary antibody dilution: 1/8000 Exposure time: 90 seconds)
Rabbit anti-Human ACADS Polyclonal Antibody | anti-ACADS antibody
ACADS Antibody
Immunohistochemistry: 1:25-1:100
Testing Data
(Gel: 10%SDS-PAGE Lysates (from left to right): Rat kidney tissue Amount of lysate: 40ug per lane Primary antibody: 1/350 dilution Secondary antibody dilution: 1/8000 Exposure time: 90 seconds)
Testing Data
(Gel: 10%SDS-PAGE Lysates (from left to right): Rat kidney tissue Amount of lysate: 40ug per lane Primary antibody: 1/350 dilution Secondary antibody dilution: 1/8000 Exposure time: 90 seconds)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue using at dilution 1/15.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue using at dilution 1/15.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a tetrameric mitochondrial flavoprotein, which is a member of the acyl-CoA dehydrogenase family. This enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Mutations in this gene have been associated with short-chain acyl-CoA dehydrogenase (SCAD) deficiency. Alternative splicing results in two variants which encode different isoforms. [provided by RefSeq, Oct 2014]
Uniprot Description
ACADS: Defects in ACADS are the cause of acyl-CoA dehydrogenase short-chain deficiency (ACADSD). It is an autosomal recessive disorder resulting in acute acidosis and muscle weakness in infants, and a form of lipid-storage myopathy in adults. Belongs to the acyl-CoA dehydrogenase family.
Protein type: Mitochondrial; EC 1.3.8.1; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Oxidoreductase; Carbohydrate Metabolism - butanoate; Lipid Metabolism - fatty acid
Chromosomal Location of Human Ortholog: 12q24.31
Cellular Component: mitochondrion; mitochondrial matrix; mitochondrial membrane; nucleus
Molecular Function: acyl-CoA dehydrogenase activity; butyryl-CoA dehydrogenase activity; FAD binding; acyl-CoA binding
Biological Process: response to starvation; fatty acid beta-oxidation; response to glucocorticoid stimulus; cellular lipid metabolic process; fatty acid beta-oxidation using acyl-CoA dehydrogenase; butyrate catabolic process; protein homotetramerization
Disease: Acyl-coa Dehydrogenase, Short-chain, Deficiency Of
Research Articles on ACADS
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Product Notes
The ACADS acads (Catalog #AAA9400978) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ACADS Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ACADS can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western blotting: 1:200-1:1000 Immunohistochemistry: 1:25-1:100. Researchers should empirically determine the suitability of the ACADS acads for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ACADS, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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