Rabbit ABT1 Polyclonal Antibody | anti-ABT1 antibody

Anti-ABT1 Antibody

Cat. Num. AAA416393

• Gene Names: ABT1; hABT1
• Reactivity: Human. Predicted: Mouse, Rat.
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity purified
• Synonyms: ABT1; Polyclonal Antibody; Anti-ABT1 Antibody; anti-ABT1 antibody

• Host: Rabbit
• Reactivity: Human. Predicted: Mouse, Rat.
• Clonality: Polyclonal
• Purity/Purification: Affinity purified
• Form/Format: Liquid
• Concentration: 100ug/100ul (varies by lot)
• Sequence Length: 272

• Applicable Applications for anti-ABT1 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: ELISA titer: 1:20,000-1:80,000; Western blot analysis: 1:1,000-1:2,000; Immunohistochemistry: 1:100-1:500; Optimal dilutions/concentrations should be determined by the end user.
• Storage Buffer: PBS, pH 7.4 with 0.02% Sodium Azide
• Immunogen: Rabbit polyclonal ABT1 (1) antibody was raised against a recombinate human ABT1 protein 2-272aa (BC066313).
• Preparation and Storage: This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Testing Data

Related Product Information for anti-ABT1 antibody

Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) with the core region of class II promoters. Studies in mouse suggest that the protein encoded by this gene likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA. [provided by RefSeq, Jul 2008]

References

(1) de Planell-Saguer,M., Schroeder,D.G., Rodicio,M.C. et al. Biochemical and genetic evidence for a role of IGHMBP2 in the translational machinery. Hum. Mol. Genet. 18 (12), 2115-2126 (2009).

NCBI and Uniprot Product Information

• NCBI GI #: 7019319
• NCBI GeneID: 29777
• NCBI Accession #: NP_037507.1
• NCBI GenBank Nucleotide #: NM_013375.3
• Molecular Weight: 31,079 Da
• NCBI Official Full Name: activator of basal transcription 1
• NCBI Official Synonym Full Names: activator of basal transcription 1
• NCBI Official Symbol: ABT1
• NCBI Official Synonym Symbols: hABT1
• NCBI Protein Information: activator of basal transcription 1; TATA-binding protein-binding protein; basal transcriptional activator
• UniProt Protein Name: Activator of basal transcription 1
• Protein Family: Activator of basal transcription
• UniProt Gene Name: ABT1
• UniProt Entry Name: ABT1_HUMAN

NCBI Description

Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) with the core region of class II promoters. Studies in mouse suggest that the protein encoded by this gene likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA. [provided by RefSeq, Jul 2008]

Uniprot Description

ABT1: Could be a novel TATA-binding protein (TBP) which can function as a basal transcription activator. Can act as a regulator of basal transcription for class II genes. Belongs to the ESF2/ABP1 family.

Protein type: Nucleolus; Transcription factor; RNA-binding

Chromosomal Location of Human Ortholog: 6p22.2

Cellular Component: transcription factor complex; nucleolus; nucleus

Molecular Function: protein binding; DNA binding; transcription coactivator activity; nucleotide binding

Biological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; spinal cord motor neuron differentiation