Western Blot (WB)
(Western blot analysis of extracts from HL60 cells using phospho-ABL1/2-Y393/429 antibody and the same antibody preincubated with blocking peptide.)
Rabbit anti-Human, Mouse ABL1/2 Polyclonal Antibody | anti-ABL1/2 antibody
ABL1/2, Phosphorylated (Y393/429) (ABL, JTK7, p150, c-ABL, v-abl, bcr/abl/ ARG, ABLL) (AP)
WB: 1:500-1:1000
Applications are based on unconjugated antibody.
Western Blot (WB)
(Western blot analysis of extracts from HL60 cells using phospho-ABL1/2-Y393/429 antibody and the same antibody preincubated with blocking peptide.)
Western Blot (WB)
(Western blot analysis of extracts from HL60 cells using phospho-ABL1/2-Y393/429 antibody and the same antibody preincubated with blocking peptide.)
NCBI and Uniprot Product Information
NCBI Description
This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR; MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons. [provided by RefSeq, Aug 2014]
Research Articles on ABL1/2
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Product Notes
The ABL1/2 (Catalog #AAA6405123) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ABL1/2, Phosphorylated (Y393/429) (ABL, JTK7, p150, c-ABL, v-abl, bcr/abl/ ARG, ABLL) (AP) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ABL1/2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB). IHC: 1:50-1:100 WB: 1:500-1:1000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the ABL1/2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ABL1/2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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