anti-Human ABCG2 Polyclonal Antibody | anti-ABCG2 antibody
Anti - ABCG2 (ATP-binding Cassette (ABC) Transporter 2)
Gene Names
ABCG2; MRX; MXR; ABCP; BCRP; BMDP; MXR1; ABC15; BCRP1; CD338; CDw338; EST157481; MGC102821
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Purified by immunoaffinity chromatography.
Synonyms
ABCG2; Polyclonal Antibody; Anti - ABCG2 (ATP-binding Cassette (ABC) Transporter 2); ABCG2 (ATP-binding Cassette (ABC) Transporter 2); anti-ABCG2 antibody
Host
Host: Rabbit
Source: Human
Source: Human
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Human control peptide is 100% conserved in Chimp, and 85% in monkey ABCG2, and only 42% in rat and 28% in mouse ABCG2.
Purity/Purification
Purified by immunoaffinity chromatography.
Form/Format
Affinity Purified
Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide, before the addition of glycerol to 40%.
Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide, before the addition of glycerol to 40%.
Concentration
~1mg/ml (varies by lot)
Sequence Length
655
Applicable Applications for anti-ABCG2 antibody
ELISA, Western Blot
Application Notes
Suitable for use in Western Blot and ELISA. Other applications not tested.
Dilution: Western Blot: 1-10ug/ml using ECL technique.
ELISA: Control peptide can be used to coat ELISA plates at 1ug/ml and detected with antibodies (0.5-1ug/ml).
Optimal dilution determined by the researcher.
Dilution: Western Blot: 1-10ug/ml using ECL technique.
ELISA: Control peptide can be used to coat ELISA plates at 1ug/ml and detected with antibodies (0.5-1ug/ml).
Optimal dilution determined by the researcher.
Immunogen
14-aa peptide from Human ABCG2 conjugated to KLH ~C-terminus, Extracellular domain
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-ABCG2 antibody
The ATP binding cassette (ABC) superfamily of membrane transporters is one of the largest protein classes known, and counts for numerous proteins involved in trafficking of biological molecules across membranes, host-defense mechanism to xenobiotics. The first known members were P-glycoprotein (P-gp) and multidrug resistant protein (MRP), cause multidrug resistance when transfected into drug-sensitive cells. In addition, increasing numbers of ABC proteins have recently been identified. The human ABCG1 (ABC, subfamily G, member 1) gene encodes a member of ABC superfamily that mediates the ATP-dependent translocation of variety of amphiphilic and lipophilic molecules. ABCG proteins were able to transport substances across cellular membranes and against concentration gradient they require an input of energy, which requires the hydrolysis of ATP, directly or indirectly.
Product Categories/Family for anti-ABCG2 antibody
References
• Csilla Ozvegy et al (2002) JBC, Vol. 277, No: 50, 47980-47980; Lyn Mickley et al (2001) Mammalian Genome 12, 86-88; L. Austin Doyle (1998) PNAS Vol. 95, 15665-15670.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
72,314 Da
NCBI Official Full Name
ATP-binding cassette sub-family G member 2
NCBI Official Synonym Full Names
ATP-binding cassette, sub-family G (WHITE), member 2
NCBI Official Symbol
ABCG2
NCBI Official Synonym Symbols
MRX; MXR; ABCP; BCRP; BMDP; MXR1; ABC15; BCRP1; CD338; CDw338; EST157481; MGC102821
NCBI Protein Information
ATP-binding cassette sub-family G member 2; ABC transporter; OTTHUMP00000161176; OTTHUMP00000219514; placenta specific MDR protein; mitoxantrone resistance protein; breast cancer resistance protein; ATP-binding cassette transporter G2; mitoxantrone resistance-associated protein; placenta-specific ATP-binding cassette transporter
UniProt Protein Name
ATP-binding cassette sub-family G member 2
Protein Family
UniProt Gene Name
ABCG2
UniProt Synonym Gene Names
ABCP; BCRP; BCRP1; MXR
UniProt Entry Name
ABCG2_HUMAN
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Product Notes
The ABCG2 abcg2 (Catalog #AAA619880) is an Antibody produced from Host: Rabbit Source: Human and is intended for research purposes only. The product is available for immediate purchase. The Anti - ABCG2 (ATP-binding Cassette (ABC) Transporter 2) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ABCG2 can be used in a range of immunoassay formats including, but not limited to, ELISA, Western Blot. Suitable for use in Western Blot and ELISA. Other applications not tested. Dilution: Western Blot: 1-10ug/ml using ECL technique. ELISA: Control peptide can be used to coat ELISA plates at 1ug/ml and detected with antibodies (0.5-1ug/ml). Optimal dilution determined by the researcher. Researchers should empirically determine the suitability of the ABCG2 abcg2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ABCG2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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