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Testing Data

Rabbit anti-Human, Mouse ABCB1 Polyclonal Antibody | anti-ABCB1 antibody

ABCB1 Antibody

Gene Names
ABCB1; ARABIDOPSIS THALIANA P GLYCOPROTEIN1; ATP binding cassette subfamily B1; ATP-binding cassette B1; ATPGP1; P-GLYCOPROTEIN 1; PGP1; T1J8.9; T1J8_9
Reactivity
Human, Mouse
Applications
ELISA, Western Blot
Synonyms
ABCB1; Polyclonal Antibody; ABCB1 Antibody; anti-ABCB1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Form/Format
Purified by peptide affinity column containing 1% BSA and 0.02% NaN3
Sequence Length
1286
Applicable Applications for anti-ABCB1 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes
Peptide ELISA: 1:5,000-1:10,000
WB: 1:500-1:1,000
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.

Testing Data

Testing Data
Related Product Information for anti-ABCB1 antibody
Rabbit polyclonal ABCB1 (1) antibody was raised against a peptide from intermediate residues of human ABCB1 protein.
References
(1) Tournier, N., Valette, H., Peyronneau, M.A., et al. Transport of selected PET radiotracers by human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2): an in vitro screening. J. Nucl. Med. 52 (3), 415-423 (2011).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
140,573 Da
NCBI Official Full Name
ATP binding cassette subfamily B1
NCBI Official Symbol
ABCB1
NCBI Official Synonym Symbols
ARABIDOPSIS THALIANA P GLYCOPROTEIN1; ATP binding cassette subfamily B1; ATP-binding cassette B1; ATPGP1; P-GLYCOPROTEIN 1; PGP1; T1J8.9; T1J8_9
NCBI Protein Information
ATP binding cassette subfamily B1
UniProt Protein Name
ABC transporter B family member 1
Protein Family
UniProt Gene Name
ABCB1
UniProt Synonym Gene Names
MDR1; PGP1; ABC transporter ABCB.1; AtABCB1; AtPgp1

NCBI Description

Belongs to the family of ATP-binding cassette (ABC) transporters. Also known as AtMDR1.Possibly regulates auxin-dependent responses by influencing basipetal auxin transport in the root. Exerts nonredundantly overlapping functions with the ABC transporter encoded by AT3G28860. PGP1 mediates cellular efflux of IAA and interacts with PIN genes that may confer an accelerated vectoral component to PGP-mediated transport. The non-polar localization of PGP1 at root and shoot apices, where IAA gradient-driven transport is impaired, may be required to confer directionality to auxin transport in those tissues.

Uniprot Description

Auxin efflux transporter that acts as a negative regulator of light signaling to promote hypocotyl elongation. Mediates the accumulation of chlorophyll and anthocyanin, as well as the expression of genes in response to light. Participates directly in auxin efflux and thus regulates the polar (presumably basipetal) auxin transport (from root tips to root elongating zone). Transports also some auxin metabolites such as oxindoleacetic acid and indoleacetaldehyde. Involved in diverse auxin-mediated responses including gravitropism, phototropism and lateral root formation. Confers resistance to herbicides such as dicamba, pendimethalin, oryzalin, and monosodium acid methanearsonate (MSMA), but not to herbicides such as glyphosate, atrazine, bentazon and fluazifop-p-butyl. Mediates also resistance to xenobiotics such as cycloheximide and the cytokinin N6-(2-isopentenyl)adenine (2IP).

Research Articles on ABCB1

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Product Notes

The ABCB1 abcb1 (Catalog #AAA855876) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ABCB1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ABCB1 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Peptide ELISA: 1:5,000-1:10,000 WB: 1:500-1:1,000. Researchers should empirically determine the suitability of the ABCB1 abcb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ABCB1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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