Rabbit anti-Human ABCA6 Polyclonal Antibody | anti-ABCA6 antibody

ABCA6 Polyclonal Antibody

Cat. Num. AAA2561418

• Gene Names: ABCA6; EST155051
• Reactivity: Human
• Applications: Immunohistochemistry, ELISA
• Purity: Antigen Affinity Purification
• Synonyms: ABCA6; Polyclonal Antibody; ABCA6 Polyclonal Antibody; ABC transporter ABCA6; ABCA 6; ATP binding cassette A6; ATP binding cassette sub family A (ABC1) member 6; ATP binding cassette sub family A member 6; ATP-binding cassette sub-family A member 6; EST155051; FLJ43498; anti-ABCA6 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purification
• Form/Format: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
• Concentration: 0.9mg/mL (varies by lot)
• Sequence Length: 1617

• Applicable Applications for anti-ABCA6 antibody: Immunohistochemistry (IHC), ELISA (EIA)
• Application Notes: IHC: 1:30-1:150; ELISA: 1:5000-1:10000
• Immunogen: Synthetic peptide of human ABCA6
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human tonsil tissue using ABCA6 Polyclonal Antibody at dilution of 1:40(×200))

Related Product Information for anti-ABCA6 antibody

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24 and may play a role in macrophage lipid homeostasis.ABCA6 (ATP Binding Cassette Subfamily A Member 6) is a Protein Coding gene. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and CDK-mediated phosphorylation and removal of Cdc6. GO annotations related to this gene include ATPase activity and ATPase activity, coupled to transmembrane movement of substances. An important paralog of this gene is ABCA8.

Product Categories/Family for anti-ABCA6 antibody

Cardiovascular; Metabolism; Signal transduction

NCBI and Uniprot Product Information

• NCBI GI #: 27436953
• NCBI GeneID: 23460
• NCBI Accession #: NP_525023.2
• NCBI GenBank Nucleotide #: NP_525023.2
• UniProt Accession #: Q8N139
• NCBI Official Full Name: ATP-binding cassette sub-family A member 6
• NCBI Official Synonym Full Names: ATP binding cassette subfamily A member 6
• NCBI Official Symbol: ABCA6
• NCBI Official Synonym Symbols: EST155051
• NCBI Protein Information: ATP-binding cassette sub-family A member 6
• UniProt Protein Name: ATP-binding cassette sub-family A member 6
• Protein Family: ABC transporter A family
• UniProt Gene Name: ABCA6
• UniProt Entry Name: ABCA6_HUMAN

NCBI Description

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24 and may play a role in macrophage lipid homeostasis. [provided by RefSeq, Jul 2008]

Uniprot Description

ABCA6: Probable transporter which may play a role in macrophage lipid homeostasis. Belongs to the ABC transporter superfamily. ABCA family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter, ABC family; Membrane protein, integral; Membrane protein, multi-pass; Transporter

Chromosomal Location of Human Ortholog: 17q24.3

Cellular Component: integral to membrane

Molecular Function: transporter activity; ATPase activity; ATP binding

Biological Process: metabolic process; transport