Western Blot (WB)
(Western Blot: Sample: Recombinant ADAMTS7, Mouse.)
Rabbit anti-Mouse A Disintegrin And Metalloproteinase With Thrombospondin 7 (ADAMTS7) Polyclonal Antibody | anti-ADAMTS7 antibody
Polyclonal Antibody to A Disintegrin And Metalloproteinase With Thrombospondin 7 (ADAMTS7)
MGHHHHHHSG S-VLPG VLYDVNHQCR LQYGSHSAYC EDMDDVCHTL WCSVGTTCHS KLDAAVDGTS CGKNKWCLKG ECVPEGFQPE AVDGGWSGWS AWSDCSRSCG VGVRSSERQC TQPVPKNRGK YCVGERKRSQ LCNLPACP
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Recombinant ADAMTS7, Mouse.)
Western Blot (WB)
(Western Blot: Sample: Recombinant ADAMTS7, Mouse.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Stomach Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Stomach Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Uterus Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Uterus Tissue.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular biology. The encoded preproprotein undergoes proteolytic processing to generate an active, zinc-dependent enzyme that degrades cartilage oligomeric matrix protein. The deficiency of the encoded protein decreases atherosclerosis in genetically hyperlipidemic mice and in response to vascular injury. Alternative splicing results in multiple transcript variants encoding different isoforms, some of which may undergo similar processing. [provided by RefSeq, May 2016]
Uniprot Description
ADAMTS7: Metalloprotease that may play a role in the degradation of COMP.
Protein type: Cell surface; EC 3.4.24.-; Motility/polarity/chemotaxis; Protease; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 9|9 E3.1
Cellular Component: cell surface; extracellular region; extracellular space; proteinaceous extracellular matrix
Molecular Function: hydrolase activity; metal ion binding; metalloendopeptidase activity; metallopeptidase activity; peptidase activity; zinc ion binding
Biological Process: negative regulation of chondrocyte differentiation; proteolysis; proteolysis involved in cellular protein catabolic process
Research Articles on ADAMTS7
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Product Notes
The ADAMTS7 adamts7 (Catalog #AAA2006157) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to A Disintegrin And Metalloproteinase With Thrombospondin 7 (ADAMTS7) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's A Disintegrin And Metalloproteinase With Thrombospondin 7 (ADAMTS7) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the ADAMTS7 adamts7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSG S-VLPG VLYDVNHQCR LQYGSHSAYC EDMDDVCHTL WCSVGTTCHS KLDAAVDGTS CGKNKWCLKG ECVPEGFQPE AVDGGWSGWS AWSDCSRSCG VGVRSSERQC TQPVPKNRGK YCVGERKRSQ LCNLPACP. It is sometimes possible for the material contained within the vial of "A Disintegrin And Metalloproteinase With Thrombospondin 7 (ADAMTS7), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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