Testing Data
(5HT-1F staining of paraffin embedded human cortical tissue.)
Rabbit anti-Human, Rat 5HT (Serotonin) 1F Receptor, 5HT1F R Polyclonal Antibody | anti-5HT1FR antibody
5HT (Serotonin) 1F Receptor, 5HT1F R
Gene Names
HTR1F; 5HT6; MR77; 5-HT1F; HTR1EL; 5-HT-1F
Reactivity
Human, Rat
Applications
Immunohistochemistry
Synonyms
5HT (Serotonin) 1F Receptor; 5HT1F R; Polyclonal Antibody; anti-5HT1FR antibody
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Form/Format
Affinity Purified antibody
Liquid. Phosphate buffered saline containing 0.1% sodium azide
Liquid. Phosphate buffered saline containing 0.1% sodium azide
Applicable Applications for anti-5HT1FR antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:1000-1:2000
Immunogen
Synthetic peptide-KLH conjugated 3rd cytoplasmic domain of human 5-HT1F.
Preparation and Storage
Long term: -70 degree C; Short term: 4 degree C. Repeated freeze/thaw cycles compromise the integrity of the antibody.
Testing Data
(5HT-1F staining of paraffin embedded human cortical tissue.)
Testing Data
(5HT-1F staining of paraffin embedded human cortical tissue.)
Related Product Information for anti-5HT1FR antibody
5HT1F, a Serotonin Receptor, is a member of the GPCR family (subfamily: Serotonin). Expression of 5HT1F has been reported in various brain structures, including cortex, hippocampus, trigeminal ganglia, and cerebral blood vessels. Expression in peripheral tissues is limited to uterus, mesentery, and artery. No expression has been detected in heart, kidney, liver, pancreas, or spleen.Selective 5-HT1F agonists may prove therapeutic in the treatment of migraine headache, lacking the side effects associated with the agonists of the 5-HT1B and 5-HT1D receptors.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
41,709 Da
NCBI Official Full Name
5-hydroxytryptamine receptor 1F
NCBI Official Synonym Full Names
5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
NCBI Official Symbol
HTR1F
NCBI Official Synonym Symbols
5HT6; MR77; 5-HT1F; HTR1EL; 5-HT-1F
NCBI Protein Information
5-hydroxytryptamine receptor 1F; serotonin receptor 1F
UniProt Protein Name
5-hydroxytryptamine receptor 1F
UniProt Gene Name
HTR1F
UniProt Synonym Gene Names
HTR1EL; 5-HT-1F; 5-HT1F
UniProt Entry Name
5HT1F_HUMAN
Uniprot Description
5-HT(1F): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Belongs to the G-protein coupled receptor 1 family.
Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 3p12
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: serotonin binding; serotonin receptor activity
Biological Process: synaptic transmission; G-protein signaling, coupled to cyclic nucleotide second messenger; G-protein signaling, adenylate cyclase inhibiting pathway; serotonin receptor signaling pathway
Research Articles on 5HT1FR
Similar Products
Product Notes
The 5HT1FR htr1f (Catalog #AAA556415) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The 5HT (Serotonin) 1F Receptor, 5HT1F R reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's 5HT (Serotonin) 1F Receptor, 5HT1F R can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:1000-1:2000. Researchers should empirically determine the suitability of the 5HT1FR htr1f for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "5HT (Serotonin) 1F Receptor, 5HT1F R, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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