DNA-directed RNA polymerase II subunit RPB9 (POLR2I) Recombinant Protein | POLR2I recombinant protein

Recombinant Human DNA-directed RNA polymerase II subunit RPB9 (POLR2I)

Cat. Num. AAA960796

• Gene Names: POLR2I; RPB9; hRPB14.5
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: DNA-directed RNA polymerase II subunit RPB9 (POLR2I); Recombinant Human DNA-directed RNA polymerase II subunit RPB9 (POLR2I); POLR2I recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-125, Full length protein
• Sequence: MEPDGTYEPGFVGIRFCQECNNMLYPKEDKENRILLYACRNCDYQQEADNSCIYVNKITHEVDELTQIIADVSQDPTLPRTEDHPCQKCGHKEAVFFQSHSARAEDAMRLYYVCTAPHCGHRWTE
• Sequence Length: 125

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for POLR2I recombinant protein

This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with two other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. The product of this gene has two zinc finger motifs with conserved cysteines and the subunit does possess zinc binding activity.

NCBI and Uniprot Product Information

• NCBI GI #: 5453930
• NCBI GeneID: 5438
• NCBI Accession #: NP_006224.1
• NCBI GenBank Nucleotide #: NM_006233.4
• UniProt Accession #: P36954; Q6NW05; B2R5J2
• Molecular Weight: 14,523 Da
• NCBI Official Full Name: DNA-directed RNA polymerase II subunit RPB9
• NCBI Official Synonym Full Names: RNA polymerase II subunit I
• NCBI Official Symbol: POLR2I
• NCBI Official Synonym Symbols: RPB9; hRPB14.5
• NCBI Protein Information: DNA-directed RNA polymerase II subunit RPB9
• UniProt Protein Name: DNA-directed RNA polymerase II subunit RPB9
• UniProt Gene Name: POLR2I
• UniProt Synonym Gene Names: RNA polymerase II subunit B9; RPB14.5

NCBI Description

This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with two other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. The product of this gene has two zinc finger motifs with conserved cysteines and the subunit does possess zinc binding activity. [provided by RefSeq, Jul 2008]

Uniprot Description

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template ().