Human polymerase (RNA) I polypeptide E, 53kDa ELISA Kit | POLR1E elisa kit
Human DNA-directed RNA polymerase I subunit RPA49, POLR1E ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
POLR1E: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Appears to be involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and UBTF/UBF. Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Nucleolus; Nucleotide Metabolism - pyrimidine; Nucleotide Metabolism - purine
Chromosomal Location of Human Ortholog: 9p13.2
Cellular Component: nucleoplasm; nucleolus; nucleus; DNA-directed RNA polymerase I complex
Molecular Function: DNA binding
Biological Process: negative regulation of gene expression, epigenetic; RNA elongation from RNA polymerase I promoter; transcription from RNA polymerase I promoter; gene expression; transcription initiation from RNA polymerase I promoter; termination of RNA polymerase I transcription; regulation of gene expression, epigenetic; rRNA transcription
Research Articles on POLR1E
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Product Notes
The Human POLR1E polr1e (Catalog #AAA9334371) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9334371 ELISA Kit recognizes Human POLR1E. It is sometimes possible for the material contained within the vial of "polymerase (RNA) I polypeptide E, 53kDa, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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