Rat polymerase (RNA) I polypeptide B, 128kDa ELISA Kit | POLR1B elisa kit
Rat DNA-directed RNA polymerase I subunit RPA2, POLR1B ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
mouse homolog is the second largest subunit of RNA polymerase I [RGD, Feb 2006]
Uniprot Description
POLR1B: a subunit of RNA polymerase I (Pol I), a DNA-dependent RNA polymerase that synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the clef. Two alternatively spliced human isoforms have been described.
Protein type: Nucleolus; EC 2.7.7.6; Transcription initiation complex; Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine; Transferase
Cellular Component: cytoplasm; nucleolus; nucleus; DNA-directed RNA polymerase I complex
Molecular Function: DNA binding; DNA-directed RNA polymerase activity; ribonucleoside binding; metal ion binding
Biological Process: nucleologenesis; transcription from RNA polymerase I promoter; embryo implantation; rRNA transcription
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Product Notes
The Rat POLR1B polr1b (Catalog #AAA9329105) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9329105 ELISA Kit recognizes Rat POLR1B. It is sometimes possible for the material contained within the vial of "polymerase (RNA) I polypeptide B, 128kDa, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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