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Typical Testing Data/Standard Curve (for reference only)

Human DNA polymerase alpha subunit B ELISA Kit | POLA2 elisa kit

Human DNA polymerase alpha subunit B ELISA Kit

Reactivity
Human
Synonyms
DNA polymerase alpha subunit B; Human DNA polymerase alpha subunit B ELISA Kit; DNA polymerase alpha 70 kDa subunit; POLA2; POLA2 elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Sequence Length
598
Assay Type
Sandwich
Detection Range
0.312-20 ng/mL
Sensitivity
0.194 ng/mL
Intra-Assay CV
<=9.4%
Inter-Assay CV
<=10.1%
Recovery
83%
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
40,579 Da
NCBI Official Full Name
DNA polymerase alpha subunit B
NCBI Official Synonym Full Names
polymerase (DNA) alpha 2, accessory subunit
NCBI Official Symbol
POLA2
NCBI Protein Information
DNA polymerase alpha subunit B
UniProt Protein Name
DNA polymerase alpha subunit B
Protein Family
UniProt Gene Name
POLA2
UniProt Entry Name
DPOA2_HUMAN

Uniprot Description

POLA2: a DNA polymerase that may play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery. DNA polymerase alpha-primase is a four subunit enzyme (subunits A, B, C and D), which is assembled throughout the cell cycle. The largest subunit (subunit A) has DNA polymerase activity, the two smallest subunits (subunits C and D) have DNA primase activity. Subunit B binds to subunit A. Phosphorylated in a cell cycle-dependent manner, in G2/M phase.

Protein type: Nucleotide Metabolism - purine; DNA replication; Nucleotide Metabolism - pyrimidine

Chromosomal Location of Human Ortholog: 11q13.1

Cellular Component: alpha DNA polymerase:primase complex; cytoplasm; nucleoplasm

Molecular Function: DNA binding; DNA-directed DNA polymerase activity; protein heterodimerization activity

Biological Process: DNA replication; DNA replication initiation; DNA strand elongation during DNA replication; G1/S transition of mitotic cell cycle; mitotic cell cycle; protein import into nucleus, translocation; telomere maintenance; telomere maintenance via recombination; telomere maintenance via semi-conservative replication

Research Articles on POLA2

Similar Products

Product Notes

The Human POLA2 pola2 (Catalog #AAA2883672) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2883672 ELISA Kit recognizes Human POLA2. It is sometimes possible for the material contained within the vial of "DNA polymerase alpha subunit B, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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