Mouse patatin-like phospholipase domain containing 3 ELISA Kit | PNPLA3 elisa kit
Mouse Patatin-like phospholipase domain-containing protein 3, PNPLA3 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
PNPLA3: Multifunctional enzyme which has both triacylglycerol lipase and acylglycerol O-acyltransferase activities. Genetic variations in PNPLA3 are a cause of susceptibility to non-alcoholic fatty liver disease type 1 (NAFLD1). A condition characterized by an accumulation of excess triglyceride in the liver, a condition known as hepatic steatosis (or fatty liver), which is associated with adverse metabolic consequences, including insulin resistance and dyslipidemia. In a subset of individuals, hepatic steatosis promotes an inflammatory response in the liver, referred to as steatohepatitis, which can progress to cirrhosis and liver cancer. NAFLD is the most common form of liver disease in Western countries. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Amino Acid Metabolism - tyrosine; Lipid Metabolism - glycerophospholipid; Transferase; Amino Acid Metabolism - phenylalanine; Phospholipase; EC 3.1.1.3; Lipid Metabolism - glycerolipid; Secondary Metabolites Metabolism - limonene and pinene degradation; Membrane protein, integral
Cellular Component: membrane; integral to membrane
Molecular Function: phospholipase A2 activity; triacylglycerol lipase activity; keto acid formate lyase activity; glucosaminyl-phosphotidylinositol O-acyltransferase activity; S-malonyltransferase activity; 3-hydroxybutyryl-CoA thiolase activity; S-acetyltransferase activity; O-octanoyltransferase activity; O-sinapoyltransferase activity; acyl-CoA N-acyltransferase activity; peptidyl-lysine N6-myristoyltransferase activity; palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity; peptidyl-lysine N6-palmitoyltransferase activity; azetidine-2-carboxylic acid acetyltransferase activity; succinyltransferase activity; dihydrolipoamide branched chain acyltransferase activity; Ras palmitoyltransferase activity; palmitoyltransferase activity; C-acyltransferase activity; C-palmitoyltransferase activity; dihydrolipoamide S-acyltransferase activity; N-acetyltransferase activity; protein-cysteine S-acyltransferase activity; serine O-acyltransferase activity; malonyltransferase activity; O-succinyltransferase activity; octanoyltransferase activity; O-palmitoyltransferase activity; hydrolase activity; 3-ketopimelyl-CoA thiolase activity; carnitine O-acyltransferase activity; sterol O-acyltransferase activity; S-succinyltransferase activity; N-acyltransferase activity; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity; O-acyltransferase activity; N-palmitoyltransferase activity; acylglycerol O-acyltransferase activity; O-acetyltransferase activity; transferase activity; benzoyl acetate-CoA thiolase activity; sinapoyltransferase activity; mono-olein transacylation activity; S-acyltransferase activity; protein-cysteine S-myristoyltransferase activity; acetyltransferase activity; myristoyltransferase activity; N-succinyltransferase activity; transferase activity, transferring acyl groups; L-2-aminoadipate N-acetyltransferase activity; diolein transacylation activity
Biological Process: metabolic process; triacylglycerol catabolic process; triacylglycerol biosynthetic process; lipid metabolic process; lipid catabolic process
Research Articles on PNPLA3
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Product Notes
The Mouse PNPLA3 pnpla3 (Catalog #AAA9337027) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9337027 ELISA Kit recognizes Mouse PNPLA3. It is sometimes possible for the material contained within the vial of "patatin-like phospholipase domain containing 3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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