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Human Polycystic kidney disease and receptor for egg jelly-related protein ELISA Kit | PKDREJ elisa kit

Human Polycystic kidney disease and receptor for egg jelly-related protein (PKDREJ) ELISA Kit

Reactivity
Human
Synonyms
Polycystic kidney disease and receptor for egg jelly-related protein; Human Polycystic kidney disease and receptor for egg jelly-related protein (PKDREJ) ELISA Kit; PKDREJ elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Specificity
This assay has high sensitivity and excellent specificity for detection of Human PKDREJ. No significant cross-reactivity or interference between Human PKDREJ and analogues was observed.
Sequence Length
2253
Samples
Serum, plasma and other biological fluids
Assay Type
Quantitative Competitive
Detection Range
0.1 ng/mL - 20 ng/mL
Sensitivity
0.1 ng/mL
Intra-assay Precision
Intra-assay Precision (Precision within an assay) Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision. Intra-Assay: CV<8%
Inter-assay Precision
Inter-assay Precision (Precision between assays) Three samples of known concentration were tested in forty separate assays to assess inter-assay precision. CV(%) = SD/meanX100. Inter-Assay: CV<12%
Preparation and Storage
Store at 2-8 degree C.
Related Product Information for PKDREJ elisa kit
Intended Uses: For the quantitative detection of Human Polycystic kidney disease and receptor for egg jelly-related protein (PKDREJ) concentration in serum, plasma and other biological fluids.

Principle of the Assay: This assay employs the competitive enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with goat-anti-rabbit antibody. Standards or samples are added to the appropriate microtiter plate wells with an antibody specific for PKDREJ and Horseradish Peroxidase (HRP) conjugated PKDREJ. The competitive inhibition reaction is launched between with HRP labeled PKDREJ and unlabeled PKDREJ with the antibody. A substrate solution is added to the wells and the color develops in opposite to the amount of PKDREJ in the sample. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
255,449 Da
NCBI Official Full Name
polycystic kidney disease and receptor for egg jelly-related protein
NCBI Official Synonym Full Names
polycystin family receptor for egg jelly
NCBI Official Symbol
PKDREJ
NCBI Protein Information
polycystic kidney disease and receptor for egg jelly-related protein
UniProt Protein Name
Polycystic kidney disease and receptor for egg jelly-related protein
UniProt Gene Name
PKDREJ

NCBI Description

This intronless gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a receptor for egg jelly (REJ) domain, a G-protein-coupled receptor proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may play a role in human reproduction. Alternative splice variants have been described but their biological natures have not been determined. [provided by RefSeq, Jul 2008]

Uniprot Description

PKDREJ: May have a central role in fertilization. May generate a Ca(2+) transporting channel directly involved in initiating the acrosome reaction of the sperm. Belongs to the polycystin family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 22q13.31

Cellular Component: integral component of membrane; membrane

Molecular Function: calcium channel activity; calcium ion binding

Biological Process: acrosome reaction; detection of mechanical stimulus

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Product Notes

The Human PKDREJ pkdrej (Catalog #AAA281636) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA281636 ELISA Kit recognizes Human PKDREJ. It is sometimes possible for the material contained within the vial of "Polycystic kidney disease and receptor for egg jelly-related protein, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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