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Aquaporin PIP2-1 (PIP2-1) Recombinant Protein | PIP2A recombinant protein

Recombinant Arabidopsis thaliana Aquaporin PIP2-1 (PIP2-1)

Gene Names
PIP2A; PIP2; PIP2;1; PIP2A; PLASMA MEMBRANE INTRINSIC PROTEIN 2; PLASMA MEMBRANE INTRINSIC PROTEIN 2;1; plasma membrane intrinsic protein 2A
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Aquaporin PIP2-1 (PIP2-1); Recombinant Arabidopsis thaliana Aquaporin PIP2-1 (PIP2-1); Recombinant Aquaporin PIP2-1 (PIP2-1); Aquaporin PIP2-1; Plasma membrane intrinsic protein 2-1; AtPIP2;1 Plasma membrane intrinsic protein 2a; PIP2a; PIP2A recombinant protein
Ordering
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2-287
Sequence
AKDVEAVPGEGFQTRDYQDPPPAPFIDGAELKKWSFYRAVIAEFVATLLFLYITVLTVIGYKIQSDTDAGGVDCGGVGILGIAWAFGGMIFILVYCTAGISGGHINPAVTFGLFLARKVSLPRALLYIIAQCLGAICGVGFVKAFQSSYYTRYGGGANSLADGYSTGTGLAAEIIGTFVLVYTVFSATDPKRSARDSHVPVLAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIYNKSKPWDDHWIFWVGPFIGAAIAAFYHQFVLRASGSKSLGSFRSAANV
Sequence Length
287
Species
Arabidopsis thaliana (Mouse-ear cress)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
30,474 Da
NCBI Official Full Name
aquaporin PIP2-1
NCBI Official Symbol
PIP2A
NCBI Official Synonym Symbols
PIP2; PIP2;1; PIP2A; PLASMA MEMBRANE INTRINSIC PROTEIN 2; PLASMA MEMBRANE INTRINSIC PROTEIN 2;1; plasma membrane intrinsic protein 2A
NCBI Protein Information
aquaporin PIP2-1
UniProt Protein Name
Aquaporin PIP2-1
UniProt Gene Name
PIP2-1
UniProt Synonym Gene Names
PIP2A; AtPIP2;1; PIP2a
UniProt Entry Name
PIP21_ARATH

NCBI Description

a member of the plasma membrane intrinsic protein subfamily PIP2. localizes to the plasma membrane and exhibits water transport activity in Xenopus oocyte. expressed specifically in the vascular bundles and protein level increases slightly during leaf dev. When expressed in yeast cells can conduct hydrogen peroxide into those cells.

Uniprot Description

Function: Water channel required to facilitate the transport of water across cell membrane. Probably involved in root water uptake. Its function is impaired by Hg2+. Ref.1

Subcellular location: Cell membrane; Multi-pass membrane protein. Note: A fuzzy intracellular localization is induced by salt (NaCl) treatment. Ref.7 Ref.11

Tissue specificity: Predominantly expressed in roots and green siliques. Also expressed at lower level above ground and in flower buds. Ref.1 Ref.8

Domain: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).

Post-translational modification: Ubiquitinated by RMA1, leading to proteasomal degradation. Ref.12The phosphorylation at Ser-280 and Ser-283 is altered by salt (NaCl) and hydrogen peroxide H2O2 treatments. Phosphorylation of Ser-283 is required for plasma membrane targeting.

Sequence similarities: Belongs to the MIP/aquaporin (TC 1.A.8) family. PIP (TC 1.A.8.11) subfamily. [View classification]

Research Articles on PIP2A

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Product Notes

The PIP2A pip2-1 (Catalog #AAA1064184) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-287. The amino acid sequence is listed below: AKDVEAVPGE GFQTRDYQDP PPAPFIDGAE LKKWSFYRAV IAEFVATLLF LYITVLTVIG YKIQSDTDAG GVDCGGVGIL GIAWAFGGMI FILVYCTAGI SGGHINPAVT FGLFLARKVS LPRALLYIIA QCLGAICGVG FVKAFQSSYY TRYGGGANSL ADGYSTGTGL AAEIIGTFVL VYTVFSATDP KRSARDSHVP VLAPLPIGFA VFMVHLATIP ITGTGINPAR SFGAAVIYNK SKPWDDHWIF WVGPFIGAAI AAFYHQFVLR ASGSKSLGSF RSAANV. It is sometimes possible for the material contained within the vial of "Aquaporin PIP2-1 (PIP2-1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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