Paired immunoglobulin-like type 2 receptor beta (Pilrb) Recombinant Protein | Pilrb recombinant protein
Recombinant Mouse Paired immunoglobulin-like type 2 receptor beta (Pilrb), partial
Gene Names
Pilrb1; Fdact; Pilrb; FDFACT
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Paired immunoglobulin-like type 2 receptor beta (Pilrb); Recombinant Mouse Paired immunoglobulin-like type 2 receptor beta (Pilrb); partial; Pilrb recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
29-195
Sequence
GN SERYNRKNGF GVNQPERCSG VQGGSIDIPF SFYFPWKLAK DPQMSIAWKW KDFHGEVIYN SSLPFIHEHF KGRLILNWTQ GQTSGVLRIL NLKESDQAQY FSRVNLQSTE GMKLWQSIPG TQLNVTQALN TTMRSPFIVT SEFTTAGLEH TSDQRNPSLM NLGAM
Sequence Length
167
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Pilrb recombinant protein
Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the non-ITIM-bearing member of the receptor pair, which has a truncated cytoplasmic tail relative to its ITIM-bearing partner and functions in the activating role. Alternative splicing has been observed at this locus and three variants, encoding two distinct isoforms, are described. Additional transcript variants have been identified but their full-length nature has not been determined.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
25,200 Da
NCBI Official Full Name
paired immunoglobulin-like type 2 receptor beta
NCBI Official Synonym Full Names
paired immunoglobin-like type 2 receptor beta 1
NCBI Official Symbol
Pilrb1
NCBI Official Synonym Symbols
Fdact; Pilrb; FDFACT
NCBI Protein Information
paired immunoglobulin-like type 2 receptor beta
UniProt Protein Name
Paired immunoglobulin-like type 2 receptor beta
Protein Family
UniProt Gene Name
Pilrb
UniProt Synonym Gene Names
Fdfact; Pilrb1
Uniprot Description
Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRB is thought to act as a cellular signaling activating receptor that associates with ITAM-bearing adapter molecules on the cell surface. Seems to associate with DAP12 and is a receptor for CD99. May be involved in target cell recognition by natural killer cells and in activation of dendritic cells.
Research Articles on Pilrb
Similar Products
Product Notes
The Pilrb pilrb (Catalog #AAA1291574) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 29-195. The amino acid sequence is listed below: GN SERYNRKNGF GVNQPERCSG VQGGSIDIPF SFYFPWKLAK DPQMSIAWKW KDFHGEVIYN SSLPFIHEHF KGRLILNWTQ GQTSGVLRIL NLKESDQAQY FSRVNLQSTE GMKLWQSIPG TQLNVTQALN TTMRSPFIVT SEFTTAGLEH TSDQRNPSLM NLGAM. It is sometimes possible for the material contained within the vial of "Paired immunoglobulin-like type 2 receptor beta (Pilrb), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
