Mouse anti-Human, Mouse WBP2 Monoclonal Antibody | anti-WBP2 antibody

WBP2 Antibody (C-term)

Cat. Num. AAA9230952

• Gene Names: WBP2; WBP-2; GRAMD6
• Reactivity: Human, Mouse
• Applications: Western Blot, ELISA
• Synonyms: WBP2; Monoclonal Antibody; WBP2 Antibody (C-term); WW domain-binding protein 2; WBP-2; anti-WBP2 antibody

• Host: Mouse
• Reactivity: Human, Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Clone Number: 932CT1.3.7
• Specificity: This WBP2 antibody is generated from a mouse immunized with a recombinant protein between 1-261 amino acids from the C-terminal region of human WBP2.
• Form/Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
• Sequence Length: 216

• Applicable Applications for anti-WBP2 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:2000
• Antigen Type: Recombinant Protein
• Antigen Source: Human
• Tissue Location: Ubiquitous.
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(All lanes : Anti-WBP2 Antibody (C-term) at 1:2000 dilutionLane 1: mouse heart lysateLane 2: A549 whole cell lysateLane 3: HL-60 whole cell lysateLane 4: 293 whole cell lysateLane 5: A2058 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 28/32 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Product Categories/Family for anti-WBP2 antibody

Crown Antibodies; Primary Antibodies; Signal Transduction

References

Chen H.I.,et al.J. Biol. Chem. 272:17070-17077 (1997). Pirozzi G.,et al.J. Biol. Chem. 272:14611-14616 (1997). Burkard T.R.,et al.BMC Syst. Biol. 5:17-17 (2011).

NCBI and Uniprot Product Information

• NCBI GI #: 1060099247
• NCBI GeneID: 23558
• NCBI Accession #: NP_001317428.1
• NCBI GenBank Nucleotide #: NM_001330499.1
• UniProt Accession #: Q969T9; O95638
• Molecular Weight: 28087 Da
• NCBI Official Full Name: WW domain-binding protein 2 isoform 2
• NCBI Official Synonym Full Names: WW domain binding protein 2
• NCBI Official Symbol: WBP2
• NCBI Official Synonym Symbols: WBP-2; GRAMD6
• NCBI Protein Information: WW domain-binding protein 2
• UniProt Protein Name: WW domain-binding protein 2
• Protein Family: WW domain-binding protein
• UniProt Gene Name: WBP2
• UniProt Synonym Gene Names: WBP-2

NCBI Description

The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. The domain is involved in mediating protein-protein interactions through the binding of polyproline ligands. This gene encodes a WW domain binding protein that is a transcriptional coactivator of estrogen receptor alpha and progesterone receptor. Defects in this gene have been associated with hearing impairment. [provided by RefSeq, Jan 2017]

Uniprot Description

WBP2: Binds to the WW domain of YAP1, WWP1 and WWP2. Interacts with NEDD4.

Protein type: Cell development/differentiation; Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 17q25.1

Cellular Component: nuclear chromatin

Molecular Function: chromatin DNA binding; protein binding

Biological Process: establishment of protein localization; positive regulation of gene expression, epigenetic; positive regulation of transcription from RNA polymerase II promoter