GPI transamidase component PIG-S (PIGS) Recombinant Protein | PIGS recombinant protein
Recombinant Human GPI transamidase component PIG-S (PIGS)
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes an essential component of the multisubunit enzyme, GPI transamidase. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins. [provided by RefSeq, Jul 2008]
Uniprot Description
PIGS: Component of the GPI transamidase complex. Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates. Belongs to the PIGS family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Glycan Metabolism - glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 17p13.2
Cellular Component: endoplasmic reticulum membrane; GPI-anchor transamidase complex; membrane
Molecular Function: GPI-anchor transamidase activity; protein binding
Biological Process: attachment of GPI anchor to protein
Similar Products
Product Notes
The PIGS pigs (Catalog #AAA7026210) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-555aa; full length protein. This is a recombinant transmembrane protein expressed in a cell-free expression system. Researchers should empirically determine the suitability of the PIGS pigs for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: AAAGAAATHL EVARGKRAAL FFAAVAIVLG LPLWWKTTET YRASLPYSQI SGLNALQLRL MVPVTVVFTR ESVPLDDQEK LPFTVVHERE IPLKYKMKIK CRFQKAYRRA LDHEEEALSS GSVQEAEAML DEPQEQAEGS LTVYVISEHS SLLPQDMMSY IGPKRTAVVR GIMHREAFNI IGRRIVQVAQ AMSLTEDVLA AALADHLPED KWSAEKRRPL KSSLGYEITF SLLNPDPKSH DVYWDIEGAV RRYVQPFLNA LGAAGNFSVD SQILYYAMLG VNPRFDSASS SYYLDMHSLP HVINPVESRL GSSAASLYPV LNFLLYVPEL AHSPLYIQDK DGAPVATNAF HSPRWGGIMV YNVDSKTYNA SVLPVRVEVD MVRVMEVFLA QLRLLFGIAQ PQLPPKCLLS GPTSEGLMTW ELDRLLWARS VENLATATTT LTSLAQLLGK ISNIVIKDDV ASEVYKAVAA VQKSAEELAS GHLASAFVAS QEAVTSSELA FFDPSLLHLL YFPDDQKFAI YIPLFLPMAV PILLSLVKIF LETRKSWRKP EKTD. It is sometimes possible for the material contained within the vial of "GPI transamidase component PIG-S (PIGS), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
