Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q (PIGQ) Recombinant Protein | PIGQ recombinant protein
Recombinant Human Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q (PIGQ)
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
NCBI and Uniprot Product Information
NCBI Description
This gene is involved in the first step in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes a N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
Uniprot Description
PIGQ: Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. Belongs to the PIGQ family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Glycan Metabolism - glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Membrane protein, integral; Membrane protein, multi-pass; EC 2.4.1.198; Transferase
Chromosomal Location of Human Ortholog: 16p13.3
Cellular Component: endoplasmic reticulum membrane; glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex; integral to membrane
Molecular Function: phosphatidylinositol N-acetylglucosaminyltransferase activity
Biological Process: carbohydrate metabolic process; preassembly of GPI anchor in ER membrane
Research Articles on PIGQ
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Product Notes
The PIGQ pigq (Catalog #AAA7026207) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-760aa; full length protein. This is a recombinant transmembrane protein expressed in a cell-free expression system. Researchers should empirically determine the suitability of the PIGQ pigq for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: VLKAFFPTCC VSTDSGLLVG RWVPEQSSAV VLAVLHFPFI PIQVKQLLAQ VRQASQVGVA VLGTWCHCRQ EPEESLGRFL ESLGAVFPHE PWLRLCRERG GTFWSCEATH RQAPTAPGAP GEDQVMLIFY DQRQVLLSQL HLPTVLPDRQ AGATTASTGG LAAVFDTVAR SEVLFRSDRF DEGPVRLSHW QSEGVEASIL AELARRASGP ICLLLASLLS LVSAVSACRV FKLWPLSFLG SKLSTCEQLR HRLEHLTLIF STRKAENPAQ LMRKANTVAS VLLDVALGLM LLSWLHGRSR IGHLADALVP VADHVAEELQ HLLQWLMGAP AGLKMNRALD QVLGRFFLYH IHLWISYIHL MSPFVEHILW HVGLSACLGL TVALSLLSDI IALLTFHIYC FYVYGARLYC LKIHGLSSLW RLFRGKKWNV LRQRVDSCSY DLDQLFIGTL LFTILLFLLP TTALYYLVFT LLRLLVVAVQ GLIHLLVDLI NSLPLYSLGL RLCRPYRLAD KPTALQPRGA HLPPPQLWLP PQALLGRPVP QAVPWGAHLP LEAERGQAGL RELLARLAPP HGHSQPSALP GWHQLSWRMS CALWTLLCAP EHGRPCYHTL GLEVIGSEQM WGWPARLAAL HHWHCLPWDP LPTCCGHHGG EHSNPRCPEH CPMPTLCTQV QRVRPPQQPQ VEGWSPWGLP SGSALAVGVE GPCQDEPPSP RHPLAPSAEQ HPASGGLKQS LTPVPSGPGP SLPEPHGVYL RMFPGEVAL. It is sometimes possible for the material contained within the vial of "Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q (PIGQ), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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