Pigeon Ras GTPase-Activating-Like Protein IQGAP2 (IQGAP2) ELISA Kit | IQGAP2 elisa kit
Pigeon Ras GTPase-Activating-Like Protein IQGAP2 (IQGAP2) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the IQGAP family. The encoded protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. This protein interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. It also acts as a tumor suppressor and has been found to play a role in regulating innate antiviral responses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2017]
Uniprot Description
IQGAP2: Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin. Isoform 2 expression is enhanced in testis. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: G protein regulator, misc.; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 5q13.3
Cellular Component: filamentous actin; microtubule; microvillus; cell surface; lamellipodium; cytoplasm; actin cytoskeleton; filopodium
Molecular Function: calmodulin binding; actin filament binding; phosphatidylinositol-3,4,5-triphosphate binding; Rho GTPase binding; Rac GTPase binding; actin binding; GTPase inhibitor activity
Biological Process: small GTPase mediated signal transduction; negative regulation of catalytic activity; signal transduction
Research Articles on IQGAP2
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Product Notes
The Pigeon IQGAP2 iqgap2 (Catalog #AAA9923602) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9923602 ELISA Kit recognizes Pigeon IQGAP2. It is sometimes possible for the material contained within the vial of "Ras GTPase-Activating-Like Protein IQGAP2 (IQGAP2), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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