FAM38B Blocking Peptide | PIEZO2 blocking peptide
FAM38B Antibody (N-term) Blocking peptide
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene contains more than thirty transmembrane domains and likely functions as part of mechanically-activated (MA) cation channels. These channels serve to connect mechanical forces to biological signals. The encoded protein quickly adapts MA currents in somatosensory neurons. Defects in this gene are a cause of type 5 distal arthrogryposis. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]
Uniprot Description
FAM38B: Component of mechanosensitive channel required for rapidly adaptating mechanically activated (MA) currents in DRG neurons. Belongs to the PIEZO family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 18p11.22
Biological Process: cation transport; detection of mechanical stimulus involved in sensory perception; response to mechanical stimulus
Research Articles on PIEZO2
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Product Notes
The PIEZO2 piezo2 (Catalog #AAA9221608) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "FAM38B, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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