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Phosphoglycolate Phosphatase Recombinant Protein | PGP recombinant protein

Recombinant Human Phosphoglycolate Phosphatase

Gene Names
PGP; PGPase
Purity
Greater than 95% as determined by SDS-PAGE.
Synonyms
Phosphoglycolate Phosphatase; Recombinant Human Phosphoglycolate Phosphatase; PGP Human; Phosphoglycolate Phosphatase Human Recombinant; Phosphoglycolate phosphatase; PGP; PGPase; PGP recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Greater than 95% as determined by SDS-PAGE.
Form/Format
The PGP protein solution (0.5mg/1ml) is formulated in 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.
Sterile Filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMAAAEA GGDDARCVRL SAERAQALLA DVDTLLFDCD GVLWRGETAV PGAPEALRAL RARGKRLGFI TNNSSKTRAA YAEKLRRLGF GGPAGPGASL EVFGTAYCTA LYLRQRLAGA PAPKAYVLGS PALAAELEAV GVASVGVGPE PLQGEGPGDW LHAPLEPDVR AVVVGFDPHF SYMKLTKALR YLQQPGCLLV GTNMDNRLPL ENGRFIAGTG CLVRAVEMAA QRQADIIGKP SRFIFDCVSQ EYGINPERTV MVGDRLDTDI LLGATCGLKT ILTLTGVSTL GDVKNNQESD CVSKKKMVPD FYVDSIADLL PALQG
Sequence Length
321
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks.Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Related Product Information for PGP recombinant protein
Description: PGP produced in E Coli is a single, non-glycosylated polypeptide chain containing 345 amino acids (1-321 a.a.) and having a molecular mass of 36.5kDa. PGP is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Introduction: Phosphoglycolate phosphatase (PGP) is discovered in all tissues including red cells, lymphocytes and cultured fibroblasts (at protein level). PGP is most active in skeletal muscle and cardiac muscle. The catalytic activity of PGP is 2-phosphoglycolate + H2O = glycolate + phosphate. Diseases associated with PGP include tardive dyskinesia and polycystic kidney disease.
Product Categories/Family for PGP recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
34,006 Da
NCBI Official Full Name
phosphoglycolate phosphatase
NCBI Official Synonym Full Names
phosphoglycolate phosphatase
NCBI Official Symbol
PGP
NCBI Official Synonym Symbols
PGPase
NCBI Protein Information
phosphoglycolate phosphatase
UniProt Protein Name
Phosphoglycolate phosphatase
UniProt Gene Name
PGP
UniProt Synonym Gene Names
PGP; PGPase
UniProt Entry Name
PGP_HUMAN

Uniprot Description

PGP: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.

Protein type: Carbohydrate Metabolism - glyoxylate and dicarboxylate; EC 3.1.3.18; Phosphatase (non-protein); EC 3.1.3.48

Chromosomal Location of Human Ortholog: 16p13.3

Molecular Function: phosphoglycolate phosphatase activity; magnesium ion binding; protein tyrosine phosphatase activity

Biological Process: dephosphorylation; carbohydrate metabolic process

Research Articles on PGP

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Product Notes

The PGP pgp (Catalog #AAA146473) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSHMA AAEA GGDDARCVRL SAERAQALLA DVDTLLFDCD GVLWRGETAV PGAPEALRAL RARGKRLGFI TNNSSKTRAA YAEKLRRLGF GGPAGPGASL EVFGTAYCTA LYLRQRLAGA PAPKAYVLGS PALAAELEAV GVASVGVGPE PLQGEGPGDW LHAPLEPDVR AVVVGFDPHF SYMKLTKALR YLQQPGCLLV GTNMDNRLPL ENGRFIAGTG CLVRAVEMAA QRQADIIGKP SRFIFDCVSQ EYGINPERTV MVGDRLDTDI LLGATCGLKT ILTLTGVSTL GDVKNNQESD CVSKKKMVPD FYVDSIADLL PALQG. It is sometimes possible for the material contained within the vial of "Phosphoglycolate Phosphatase, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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