Z-VAD-FMK Peptide
Z-VAD-FMK [Pan-Caspase Specific Inhibitor (FMK)]
Purity
>=98% (HPLC)
Synonyms
Z-VAD-FMK; Z-VAD-FMK [Pan-Caspase Specific Inhibitor (FMK)]; Z-VAD-FMK peptide
Purity/Purification
>=98% (HPLC)
Form/Format
Solid
Sequence
Z-Val-Ala-Asp-fluoromethylketone
Peptide Content
77-97%
Formula
C21H28FN3O7
Solubility
Soluble in DMSO or acetonitrile (10mg/ml)
CAS Number
220644-02-0
Product Notes
Prepare a 10mM stock solution of the caspase inhibitor in high quality DMSO. Add 2ul of this stock solution to 1ml of culture medium containing cells to give 20uM final concentration. Effective final concentrations are estimated to be 5-20uM. If a particular caspase inhibitor is applied at higher concentrations specificity for an individual caspase or even for the caspase family (> 100uM) might be compromised. DMSO concentration above 0.2% may cause cellular toxicity thus masking the effect of the caspase inhibitor. For in vivo experiments extending for 12 to 48 hours, fresh inhibitor may have to be added (injected) due to inactivation by reaction with cysteine protease
Preparation and Storage
For long term storage, store at -20 degree C
Keep sealed after removing from the freezer until its temperature equilibrates with room temperature. Dissolve only the amount needed at one time because of the possibility of decomposition in solution
After reconstitution, prepare aliquots and store at -20 degree C
Keep sealed after removing from the freezer until its temperature equilibrates with room temperature. Dissolve only the amount needed at one time because of the possibility of decomposition in solution
After reconstitution, prepare aliquots and store at -20 degree C
Related Product Information for Z-VAD-FMK peptide
??Pan-Caspase Inhibitor. Z-VAD-FMK acts as an effective irreversible caspase inhibitor with no cytotoxic effects and, therefore, is a useful tool for studying caspase activity.
Product Categories/Family for Z-VAD-FMK peptide
Similar Products
Product Notes
The Z-VAD-FMK (Catalog #AAA566145) is a Peptide and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Z-Val-Ala- Asp-fluoro methylketo ne. It is sometimes possible for the material contained within the vial of "Z-VAD-FMK, Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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