p53 peptide
p53 Activator
Purity
>=97% (HPLC)
Synonyms
p53; p53 Activator; p53 peptide
Purity/Purification
>=97% (HPLC)
Form/Format
Lyophilized solid
Sequence
Gly-Ser-Arg-Ala-His-Ser-Ser-His-Leu-Lys-Ser-Lys-Lys-Gly-Gln-Ser-Thr-Ser-Arg-His-Lys-Lys-Trp-Lys-Met-Arg-Arg-Asn-Gln-Phe-Trp-Val-Lys-Val-Gln-Arg-Gly
Solubility
Soluble in water
Preparation and Storage
For long term storage, store at -20 degree C
Shipping: Shipped on Blue Ice
Shipping: Shipped on Blue Ice
Related Product Information for p53 peptide
A peptide corresponding to 'peptide 46', (aa 361-382), which corresponds to the single-stranded DNA-end binding site of p53. This sequence is an activator of wild-type and certain p53 mutants. Fusion Peptide 46, a 35-mer peptide, consists of peptide 46 linked to a sequence from the third helix of Drosophila Antennapedia homeodomain protein in order to confer cell permeability. The p53 Activator (Fusion Peptide 46) has been demonstrated to have numerous effects including: rescue of p53 growth inhibition (5ug/mL) in a human osteosarcoma Saos-2 subline transfected with His273 p53 mutant; at 20uM, it induced 56% apoptosis in Burkitt lymphoma cell line Ew36 carrying wt p53; and it induced apoptosis in mutant p53 cell lines BL41 (20%) and SW480 (25%). It has no effect in p53 null cell lines HL60 and Saos-21. The p53 activator peptide is a useful tool to study p53.
Product Categories/Family for p53 peptide
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Product Notes
The p53 (Catalog #AAA566495) is a Peptide and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Gly-Ser-Ar g-Ala-His- Ser-Ser-Hi s-Leu-Lys- Ser-Lys-Ly s-Gly-Gln- Ser-Thr-Se r-Arg-His- Lys-Lys-Tr p-Lys-Met- Arg-Arg-As n-Gln-Phe- Trp-Val-Ly s-Val-Gln- Arg-Gly. It is sometimes possible for the material contained within the vial of "p53, Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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