Mouse pellino homolog 2 (Drosophila) ELISA Kit | PELI2 elisa kit
Mouse Protein pellino homolog 2, PELI2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
PELI2: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1. Can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1. Not required for NF-kappa-B activation. Belongs to the pellino family.
Protein type: Ubiquitin conjugating system; Ubiquitin ligase; EC 6.3.2.19; Adaptor/scaffold; EC 6.3.2.-
Cellular Component: protein complex; membrane; cytosol
Molecular Function: protein binding; coenzyme F420-2 alpha-glutamyl ligase activity; UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity; ribosomal S6-glutamic acid ligase activity; coenzyme F420-0 gamma-glutamyl ligase activity; ligase activity
Biological Process: positive regulation of MAPKKK cascade; positive regulation of protein amino acid phosphorylation; Toll signaling pathway
Research Articles on PELI2
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Product Notes
The Mouse PELI2 peli2 (Catalog #AAA9322692) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9322692 ELISA Kit recognizes Mouse PELI2. It is sometimes possible for the material contained within the vial of "pellino homolog 2 (Drosophila), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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