Mouse PDZ domain containing 1 ELISA Kit | PDZK1 elisa kit

Mouse Na (+) /H (+) exchange regulatory cofactor NHE-RF3

Cat. Num. AAA9321628

• Gene Names: Pdzk1; Pdzd1; mPDZK1; AI267131; AI314638; AL022680; D3Ertd537e; 1700023D20Rik; 2610507N21Rik; 4921513F16Rik
• Reactivity: Mouse
• Synonyms: PDZ domain containing 1; Mouse Na (+) /H (+) exchange regulatory cofactor NHE-RF3; Mouse Na (+) /H (+) exchange regulatory cofactor NHE-RF3 (PDZK1) ELISA kit; CAP70; CLAMP; NHERF3; PDZD1; C-terminal linking and modulating protein; OTTHUMP00000015572; PDZK1 elisa kit

• Reactivity: Mouse

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 225579122
• NCBI GeneID: 59020
• NCBI Accession #: NP_001139473.1
• NCBI GenBank Nucleotide #: NM_001146001.1
• UniProt Accession #: Q9JIL4; Q8CDP5; Q8R4G2; Q9CQ72
• Molecular Weight: 56,499 Da
• NCBI Official Full Name: Na(+)/H(+) exchange regulatory cofactor NHE-RF3
• NCBI Official Synonym Full Names: PDZ domain containing 1
• NCBI Official Symbol: Pdzk1
• NCBI Official Synonym Symbols: Pdzd1; mPDZK1; AI267131; AI314638; AL022680; D3Ertd537e; 1700023D20Rik; 2610507N21Rik; 4921513F16Rik
• NCBI Protein Information: Na(+)/H(+) exchange regulatory cofactor NHE-RF3; Na(+)/H(+) exchange regulatory cofactor NHE-RF3; NHERF-3; naPi-Cap1; PDZ domain-containing protein 1; CFTR-associated protein of 70 kDa; Na(+)/H(+) exchanger regulatory factor 3; sodium-hydrogen exchanger regulatory factor 3; na/Pi cotransporter C-terminal-associated protein 1
• UniProt Protein Name: Na(+)/H(+) exchange regulatory cofactor NHE-RF3
• Protein Family: Na(+)/H(+) exchange regulatory cofactor
• UniProt Gene Name: Pdzk1
• UniProt Synonym Gene Names: Cap70; Nherf3; NHERF-3; NaPi-Cap1
• UniProt Entry Name: NHRF3_MOUSE

Uniprot Description

PDZK1: A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. May function to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism. May be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function. Belongs to the NHER family.

Protein type: Adaptor/scaffold

Cellular Component: membrane; microvillus membrane; brush border membrane; cytoplasm; apical plasma membrane; plasma membrane; lipid raft

Molecular Function: protein binding; scavenger receptor binding; protein complex binding; PDZ domain binding

Biological Process: transport; carnitine transport