p53 and DNA-Damage Regulated 1 Recombinant Protein | PDRG1 recombinant protein
Recombinant Human p53 and DNA-Damage Regulated 1
Sterile Filtered colorless solution.
Introduction: PDRG1 is a 133 amino acid protein that localizes to the cytoplasm and belongs to the prefoldin subunit beta family. PDRG1 is expressed primarily in normal testicular tissue, it is functionally induced by ultraviolet light and is thought to have a role in chaperone-mediated protein folding, possibly having a role in cellular degradation. PDRG1 is linked to Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome.
NCBI and Uniprot Product Information
Uniprot Description
PDRG1: May play a role in chaperone-mediated protein folding (Potential). Belongs to the prefoldin subunit beta family.
Chromosomal Location of Human Ortholog: 20q11.21
Cellular Component: cytoplasm; prefoldin complex
Molecular Function: unfolded protein binding
Biological Process: protein folding
Research Articles on PDRG1
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Product Notes
The PDRG1 pdrg1 (Catalog #AAA144260) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MLSPEAERVL RYLVEVEELA EEVLADKRQI VDLDTKRNQN REGLRALQKD LSLSEDVMVC FGNMFIKMPH PETKEMIEKD QDHLDKEIEK LRKQLKVKVN RLFEAQGKPE LKGFNLNPLN QDELKALKVI LKG. It is sometimes possible for the material contained within the vial of "p53 and DNA-Damage Regulated 1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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