Immunohistochemistry (IHC)
(Immunochemical staining of human PDRG1 in human lung cancer with rabbit polyclonal antibody (1:10000, formalin-fixed paraffin embedded sections).)
Rabbit anti-Human PDRG1 Polyclonal Antibody | anti-PDRG1 antibody
Anti-PDRG1 Antibody, Rabbit Polyclonal
Gene Names
PDRG1; PDRG; C20orf126
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
PDRG1; Polyclonal Antibody; Anti-PDRG1 Antibody; Rabbit Polyclonal; PDRG1/C20orf126 Antibody; Rabbit PAb; Antigen Affinity Purified; p53 and DNA-damage regulated 1; Anti-C20orf126 Antibody; Anti-PDRG Antibody; anti-PDRG1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human PDRG1/C20orf126
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-PDRG1 antibody
ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
ELISA: 1:5000-1:10,000
IHC-P: 1:2500-1:10,000
IHC-P: 1:2500-1:10,000
Immunogen
Recombinant Human PDRG1/C20orf126 protein
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with purified, recombinant Human PDRG1/C20orf126 (rh PDRG1/C20orf126). PDRG1/C20orf126 specific IgG was purified by Human PDRG1/C20orf126 affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of human PDRG1 in human lung cancer with rabbit polyclonal antibody (1:10000, formalin-fixed paraffin embedded sections).)
Immunohistochemistry (IHC)
(Immunochemical staining of human PDRG1 in human lung cancer with rabbit polyclonal antibody (1:10000, formalin-fixed paraffin embedded sections).)
Immunohistochemistry (IHC)
(Immunochemical staining of human PDRG1 in human testis with rabbit polyclonal antibody (1:10000, formalin-fixed paraffin embedded sections).)
Immunohistochemistry (IHC)
(Immunochemical staining of human PDRG1 in human testis with rabbit polyclonal antibody (1:10000, formalin-fixed paraffin embedded sections).)
Related Product Information for anti-PDRG1 antibody
PDRG1, also known as C2orf126, belongs to the prefoldin subunit beta family. It is predominantly expressed in normal testis and exhibits reduced but detectable expression in other organs. PDRG1 may play a role in chaperone-mediated protein folding. PDRG1 is overexpressed in tumors relative to normal tissues. Its expression is upregulated in multiple malignancies including cancers of the colon, rectum, ovary, lung, stomach, breast and uterus when compared to their respective matched normal tissues. Thus PDRG1 is a high-value novel tumor marker that could play a role in cancer development and/or progression.
References
Kim W. et al., 2011, Mol Cell. 44 (2): 325-40. Havugimana PC. et al., 2012, Cell. 150 (5): 1068-81. Jiang L. et al., 2011, Cancer Biol Ther. 11 (6): 567-73.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
15,511 Da
NCBI Official Full Name
p53 and DNA damage-regulated protein 1
NCBI Official Synonym Full Names
p53 and DNA-damage regulated 1
NCBI Official Symbol
PDRG1
NCBI Official Synonym Symbols
PDRG; C20orf126
NCBI Protein Information
p53 and DNA damage-regulated protein 1; p53 and DNA damage regulated 1
UniProt Protein Name
p53 and DNA damage-regulated protein 1
Protein Family
UniProt Gene Name
PDRG1
UniProt Synonym Gene Names
C20orf126; PDRG
UniProt Entry Name
PDRG1_HUMAN
Uniprot Description
PDRG1: May play a role in chaperone-mediated protein folding (Potential). Belongs to the prefoldin subunit beta family.
Chromosomal Location of Human Ortholog: 20q11.21
Cellular Component: cytoplasm; prefoldin complex
Molecular Function: unfolded protein binding
Biological Process: protein folding
Research Articles on PDRG1
Similar Products
Product Notes
The PDRG1 pdrg1 (Catalog #AAA8107245) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-PDRG1 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PDRG1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P). ELISA: 1:5000-1:10,000 IHC-P: 1:2500-1:10,000. Researchers should empirically determine the suitability of the PDRG1 pdrg1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PDRG1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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