Mouse Platelet-derived growth factor subunit A ELISA Kit | Pdgfa elisa kit
Mouse Platelet-derived growth factor subunit A ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
PDGFA: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal lung alveolar septum formation during embryogenesis, normal development of the gastrointestinal tract, normal development of Leydig cells and spermatogenesis. Required for normal oligodendrocyte development and normal myelination in the spinal cord and cerebellum. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFB. Belongs to the PDGF/VEGF growth factor family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide; Cell cycle regulation; Cytokine
Cellular Component: cell surface; extracellular region; extracellular space; membrane; microvillus
Molecular Function: collagen binding; growth factor activity; platelet-derived growth factor binding; platelet-derived growth factor receptor binding; protein heterodimerization activity; protein homodimerization activity
Biological Process: actin cytoskeleton organization and biogenesis; alveolus development; angiogenesis; cell projection biogenesis; gut development; hair follicle development; multicellular organismal development; negative chemotaxis; negative regulation of phosphatidylinositol biosynthetic process; organ morphogenesis; platelet-derived growth factor receptor signaling pathway; positive regulation of cell division; positive regulation of cell migration; positive regulation of cell proliferation; positive regulation of DNA replication; positive regulation of fibroblast proliferation; positive regulation of MAP kinase activity; positive regulation of MAPKKK cascade; positive regulation of mesenchymal cell proliferation; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of protein amino acid autophosphorylation; positive regulation of protein kinase B signaling cascade; regulation of peptidyl-tyrosine phosphorylation; regulation of smooth muscle cell migration; response to wounding; skin development
Research Articles on Pdgfa
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Product Notes
The Mouse Pdgfa pdgfa (Catalog #AAA2883136) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2883136 ELISA Kit recognizes Mouse Pdgfa. It is sometimes possible for the material contained within the vial of "Platelet-derived growth factor subunit A, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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