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Neuroendocrine convertase 1 (Pcsk1) Recombinant Protein | Pcsk1 recombinant protein

Recombinant Rat Neuroendocrine convertase 1 (Pcsk1)

Gene Names
Pcsk1; BDP; PC1; PC3
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Neuroendocrine convertase 1 (Pcsk1); Recombinant Rat Neuroendocrine convertase 1 (Pcsk1); Neuroendocrine convertase 1; NEC 1; EC=3.4.21.93; Prohormone convertase 1; Proprotein convertase 1; PC1; Pcsk1 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
111-752
Sequence
SVPRDSALNL FNDPMWNQQW YLQDTRMTAS LPKLDLHVIP VWQKGITGKG VVITVLDDGL EWNHTDIYAN YDPEASYDFN DNDHDPFPRY DPTNENKHGT RCAGEIAMQA NNHKCGVGVA YNSKVGGIRM LDGIVTDAIE ASSIGFNPGH VDIYSASWGP NDDGKTVEGP GRLAQKAFEY GVKQGRQGKG SIFVWASGNG GRQGDNCDCD GYTDSIYTIS ISSASQQGLS PWYAEKCSST LATSYSSGDY TDQRITSADL HNDCTETHTG TSASAPLAAG IFALALEANP NLTWRDMQHL VVWTSEYDPL ANNPGWKKNG AGLMVNSRFG FGLLNAKALV DLADPRTWRN VPEKKECIIK DNNFEPRALK ANGEVIVEIP TRACEGQENA INSLEHVQFE ATIEYSRRGD LHVTLTSAAG TSTVLLAERE RDTSPNGFKN WDFMSVHTWG ENPVGTWTLK VTDMSGRMQN EGRIVNWKLI LHGTSSQPEH MKQPRVYTSY NTVQNDRRGV EKMVNVVEEK PTQNSLNGNL LVPKNSSSSS VEDRRDEQVQ GAPSKAMLRL LQSAFSKNTP SKQSSKIPSA KLSVPYEGLY EALEKLNKPS QLEDSEDSLY SDYVDVFYNT KPYKHRDDRL LQALMDILNE KN
Sequence Length
642
Species
Rattus norvegicus (Rat)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Pcsk1 recombinant protein
Pcsk1; Bdp, Nec-1, Nec1

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
73.2 kDa
NCBI Official Full Name
neuroendocrine convertase 1
NCBI Official Synonym Full Names
proprotein convertase subtilisin/kexin type 1
NCBI Official Symbol
Pcsk1
NCBI Official Synonym Symbols
BDP; PC1; PC3
NCBI Protein Information
neuroendocrine convertase 1; NEC 1; prohormone convertase 1; prohormone convertase 3; proprotein convertase 1; Protein convertase subtilisin / kexin type I; Protein convertase subtilisin / kexin, type I
UniProt Protein Name
Neuroendocrine convertase 1
Protein Family
UniProt Gene Name
Pcsk1
UniProt Synonym Gene Names
Bdp; Nec-1; Nec1; NEC 1; PC1
UniProt Entry Name
NEC1_RAT

NCBI Description

plays a role in proteolytic processing of peptide hormone and other protein precursors [RGD, Feb 2006]

Uniprot Description

PCSK1: Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin and insulin. Belongs to the peptidase S8 family. Furin subfamily.

Protein type: Protease; EC 3.4.21.93

Cellular Component: extracellular space; neuron projection; transport vesicle; rough endoplasmic reticulum; cell soma; perinuclear region of cytoplasm; dendrite; perikaryon; nerve terminal; trans-Golgi network; secretory granule

Molecular Function: insulin binding; chaperone binding; serine-type endopeptidase activity; endopeptidase activity; protein complex binding

Biological Process: response to nutrient levels; response to drug; response to peptide hormone stimulus; response to inorganic substance; response to glucocorticoid stimulus; peptide hormone processing; response to morphine; response to lipopolysaccharide; proteolysis; response to organic cyclic substance; response to chlorate; peptide biosynthetic process; protein autoprocessing; positive regulation of protein secretion; neurogenesis; pituitary gland development; pancreas development; response to glucose stimulus; protein processing; response to axon injury; response to calcium ion

Research Articles on Pcsk1

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Product Notes

The Pcsk1 pcsk1 (Catalog #AAA948340) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 111-752. The amino acid sequence is listed below: SVPRDSALNL FNDPMWNQQW YLQDTRMTAS LPKLDLHVIP VWQKGITGKG VVITVLDDGL EWNHTDIYAN YDPEASYDFN DNDHDPFPRY DPTNENKHGT RCAGEIAMQA NNHKCGVGVA YNSKVGGIRM LDGIVTDAIE ASSIGFNPGH VDIYSASWGP NDDGKTVEGP GRLAQKAFEY GVKQGRQGKG SIFVWASGNG GRQGDNCDCD GYTDSIYTIS ISSASQQGLS PWYAEKCSST LATSYSSGDY TDQRITSADL HNDCTETHTG TSASAPLAAG IFALALEANP NLTWRDMQHL VVWTSEYDPL ANNPGWKKNG AGLMVNSRFG FGLLNAKALV DLADPRTWRN VPEKKECIIK DNNFEPRALK ANGEVIVEIP TRACEGQENA INSLEHVQFE ATIEYSRRGD LHVTLTSAAG TSTVLLAERE RDTSPNGFKN WDFMSVHTWG ENPVGTWTLK VTDMSGRMQN EGRIVNWKLI LHGTSSQPEH MKQPRVYTSY NTVQNDRRGV EKMVNVVEEK PTQNSLNGNL LVPKNSSSSS VEDRRDEQVQ GAPSKAMLRL LQSAFSKNTP SKQSSKIPSA KLSVPYEGLY EALEKLNKPS QLEDSEDSLY SDYVDVFYNT KPYKHRDDRL LQALMDILNE KN. It is sometimes possible for the material contained within the vial of "Neuroendocrine convertase 1 (Pcsk1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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