PHO85 cyclin-1 (PCL1) Recombinant Protein | PCL1 recombinant protein
Recombinant Saccharomyces cerevisiae PHO85 cyclin-1 (PCL1)
Gene Names
PCL1; HCS26
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
PHO85 cyclin-1 (PCL1); Recombinant Saccharomyces cerevisiae PHO85 cyclin-1 (PCL1); PCL1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-279, full length protein
Sequence
MCEYSKALHILLKSPVTDDIIKFLTDTTLRVVPSSNYPTPPGSPGEKHLTRLPSLMTFITRLVRYTNVYTPTLLTAACYLNKLKRILPRDATGLPSTIHRIFLACLILSAKFHNDSSPLNKHWARYTDGLFTLEDINLMERQLLQLLNWDLRVNTEDLILDLQPLLEPIKQDLARSSDQRKRINMMMSMNRRTCAGTSPIRSNNRFKLYEKQRNVSIASDLSSATLVDSCNDLRRLKDVTNIANNTVANTNYVRTVEKWNDNVNRQSWDLEQIMSQHGF
Sequence Length
279
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
32,095 Da
NCBI Official Full Name
Pcl1p
NCBI Official Symbol
PCL1
NCBI Official Synonym Symbols
HCS26
NCBI Protein Information
Pcl1p
UniProt Protein Name
PHO85 cyclin-1
Protein Family
UniProt Gene Name
PCL1
Uniprot Description
G1/S-specific cyclin partner of the cyclin-dependent kinase (CDK) PHO85. Essential for the control of the cell cycle at the G1/S (start) transition. The PCL1-PHO85 cyclin-CDK holoenzyme is involved in phosphorylation of the CDK inhibitor (CKI) SIC1, which is required for its ubiquitination and degradation, releasing repression of b-type cyclins and promoting exit from mitosis. Together with cyclin PCL2, positively controls degradation of sphingoid long chain base kinase LCB4. PCL1-PHO85 phosphorylates LCB4, which is required for its ubiquitination and degradation. PCL1-PHO85 also phosphorylates HMS1, NCP1 and NPA3, which may all have a role in mitotic exit.
Research Articles on PCL1
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Product Notes
The PCL1 pcl1 (Catalog #AAA1037978) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-279, full length protein. The amino acid sequence is listed below: MCEYSKALHI LLKSPVTDDI IKFLTDTTLR VVPSSNYPTP PGSPGEKHLT RLPSLMTFIT RLVRYTNVYT PTLLTAACYL NKLKRILPRD ATGLPSTIHR IFLACLILSA KFHNDSSPLN KHWARYTDGL FTLEDINLME RQLLQLLNWD LRVNTEDLIL DLQPLLEPIK QDLARSSDQR KRINMMMSMN RRTCAGTSPI RSNNRFKLYE KQRNVSIASD LSSATLVDSC NDLRRLKDVT NIANNTVANT NYVRTVEKWN DNVNRQSWDL EQIMSQHGF. It is sometimes possible for the material contained within the vial of "PHO85 cyclin-1 (PCL1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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