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Propionyl-CoA carboxylase beta chain, mitochondrial (PCCB) Recombinant Protein | PCCB recombinant protein

Recombinant Human Propionyl-CoA carboxylase beta chain, mitochondrial (PCCB)

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Propionyl-CoA carboxylase beta chain; mitochondrial (PCCB); Recombinant Human Propionyl-CoA carboxylase beta chain; PCCB recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
29-539, Full length protein
Sequence
CSQATSVNERIENKRRTALLGGGQRRIDAQHKRGKLTARERISLLLDPGSFVESDMFVEHRCADFGMAADKNKFPGDSVVTGRGRINGRLVYVFSQDFTVFGGSLSGAHAQKICKIMDQAITVGAPVIGLNDSGGARIQEGVESLAGYADIFLRNVTASGVIPQISLIMGPCAGGAVYSPALTDFTFMVKDTSYLFITGPDVVKSVTNEDVTQEELGGAKTHTTMSGVAHRAFENDVDALCNLRDFFNYLPLSSQDPAPVRECHDPSDRLVPELDTIVPLESTKAYNMVDIIHSVVDEREFFEIMPNYAKNIIVGFARMNGRTVGIVGNQPKVASGCLDINSSVKGARFVRFCDAFNIPLITFVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKVTVITRKAYGGAYDVMSSKHLCGDTNYAWPTAEIAVMGAKGAVEIIFKGHENVEAAQAEYIEKFANPFPAAVRGFVDDIIQPSSTRARICCDLDVLASKKVQRPWRKHANIPL
Sequence Length
511
Species
Human
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for PCCB recombinant protein
This protein is a subunit of the propionyl-CoA carboxylase (PCC) enzyme, which is involved in the catabolism of propionyl-CoA. PCC is a mitochondrial enzyme that probably acts as a dodecamer of six alpha subunits and six beta subunits. This gene encodes the beta subunit of PCC. Defects in this gene are a cause of propionic acidemia type II (PA-2).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
60,521 Da
NCBI Official Full Name
propionyl-CoA carboxylase beta chain, mitochondrial isoform 1
NCBI Official Synonym Full Names
propionyl-CoA carboxylase beta subunit
NCBI Official Symbol
PCCB
NCBI Protein Information
propionyl-CoA carboxylase beta chain, mitochondrial
UniProt Protein Name
Propionyl-CoA carboxylase beta chain, mitochondrial
Protein Family
UniProt Gene Name
PCCB
UniProt Synonym Gene Names
PCCase subunit beta

NCBI Description

The protein encoded by this gene is a subunit of the propionyl-CoA carboxylase (PCC) enzyme, which is involved in the catabolism of propionyl-CoA. PCC is a mitochondrial enzyme that probably acts as a dodecamer of six alpha subunits and six beta subunits. This gene encodes the beta subunit of PCC. Defects in this gene are a cause of propionic acidemia type II (PA-2). Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010]

Research Articles on PCCB

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Product Notes

The PCCB pccb (Catalog #AAA963732) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 29-539, Full length protein. The amino acid sequence is listed below: CSQATSVNER IENKRRTALL GGGQRRIDAQ HKRGKLTARE RISLLLDPGS FVESDMFVEH RCADFGMAAD KNKFPGDSVV TGRGRINGRL VYVFSQDFTV FGGSLSGAHA QKICKIMDQA ITVGAPVIGL NDSGGARIQE GVESLAGYAD IFLRNVTASG VIPQISLIMG PCAGGAVYSP ALTDFTFMVK DTSYLFITGP DVVKSVTNED VTQEELGGAK THTTMSGVAH RAFENDVDAL CNLRDFFNYL PLSSQDPAPV RECHDPSDRL VPELDTIVPL ESTKAYNMVD IIHSVVDERE FFEIMPNYAK NIIVGFARMN GRTVGIVGNQ PKVASGCLDI NSSVKGARFV RFCDAFNIPL ITFVDVPGFL PGTAQEYGGI IRHGAKLLYA FAEATVPKVT VITRKAYGGA YDVMSSKHLC GDTNYAWPTA EIAVMGAKGA VEIIFKGHEN VEAAQAEYIE KFANPFPAAV RGFVDDIIQP SSTRARICCD LDVLASKKVQ RPWRKHANIP L. It is sometimes possible for the material contained within the vial of "Propionyl-CoA carboxylase beta chain, mitochondrial (PCCB), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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