MCG10 Blocking Peptide | PCBP4 blocking peptide

MCG10 Peptide

Cat. Num. AAA153196

• Gene Names: PCBP4; CBP; LIP4; MCG10
• Applications: Blocking (BL)
• Synonyms: MCG10; MCG10 Peptide; CBP; LIP4; MCG10Alpha-CP4; poly(rC) binding protein 4; PCBP4 blocking peptide

• Form/Format: Liquid
• Concentration: 200 ug/mL (varies by lot)
• Sequence Length: 360

• Applicable Applications for PCBP4 blocking peptide: Blocking (BL)
• Application Notes: MCG10 peptide is used for blocking the activity of MCG10 antibody.
• Species: Human
• Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
• Location: 17 amino acids near the carboxy terminus of human MCG10C
• Preparation and Storage: Store MCG10 peptide at -20 degree C, stable for one year.

NCBI and Uniprot Product Information

• NCBI GI #: 119585570
• NCBI GeneID: 57060
• UniProt Accession #: P57723; Q96AH7
• Molecular Weight: 37,078 Da
• NCBI Official Full Name: poly(rC) binding protein 4, isoform CRA_b
• NCBI Official Synonym Full Names: poly(rC) binding protein 4
• NCBI Official Symbol: PCBP4
• NCBI Official Synonym Symbols: CBP; LIP4; MCG10
• NCBI Protein Information: poly(rC)-binding protein 4; poly(rC)-binding protein 4; alpha-CP4; LYST-interacting protein; RNA binding protein MCG10
• UniProt Protein Name: Poly(rC)-binding protein 4
• Protein Family: Poly(rC)-binding protein
• UniProt Gene Name: PCBP4
• UniProt Entry Name: PCBP4_HUMAN

NCBI Description

This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the encoded protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G(2)-M. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Multiple alternatively spliced transcript variants have been described, but the full-length nature for only some has been determined. [provided by RefSeq, Jul 2008]

Uniprot Description

PCBP4: Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 3p21

Cellular Component: cytoplasm; ribonucleoprotein complex

Molecular Function: DNA binding; RNA binding