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Probable proline--tRNA ligase, mitochondrial (PARS2) Recombinant Protein | PARS2 recombinant protein

Recombinant Human Probable proline--tRNA ligase, mitochondrial (PARS2)

Gene Names
PARS2; proRS; MT-PRORS
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Probable proline--tRNA ligase; mitochondrial (PARS2); Recombinant Human Probable proline--tRNA ligase; PARS2 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
30-475, Full length protein
Sequence
HHCAPRRGRRLLLSRVFQPQNLREDRVLSLQDKSDDLTCKSQRLMLQVGLIYPASPGCYHLLPYTVRAMEKLVRVIDQEMQAIGGQKVNMPSLSPAELWQATNRWDLMGKELLRLRDRHGKEYCLGPTHEEAITALIASQKKLSYKQLPFLLYQVTRKFRDEPRPRFGLLRGREFYMKDMYTFDSSPEAAQQTYSLVCDAYCSLFNKLGLPFVKVQADVGTIGGTVSHEFQLPVDIGEDRLAICPRCSFSANMETLDLSQMNCPACQGPLTKTKGIEVGHTFYLGTKYSSIFNAQFTNVCGKPTLAEMGCYGLGVTRILAAAIEVLSTEDCVRWPSLLAPYQACLIPPKKGSKEQAASELIGQLYDHITEAVPQLHGEVLLDDRTHLTIGNRLKDANKFGYPFVIIAGKRALEDPAHFEVWCQNTGEVAFLTKDGVMDLLTPVQTV
Sequence Length
446
Species
Human
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
53,263 Da
NCBI Official Full Name
probable proline--tRNA ligase, mitochondrial
NCBI Official Synonym Full Names
prolyl-tRNA synthetase 2, mitochondrial
NCBI Official Symbol
PARS2
NCBI Official Synonym Symbols
proRS; MT-PRORS
NCBI Protein Information
probable proline--tRNA ligase, mitochondrial
UniProt Protein Name
Probable proline--tRNA ligase, mitochondrial
UniProt Gene Name
PARS2
UniProt Synonym Gene Names
ProRS

NCBI Description

This gene encodes a putative member of the class II family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of proline to tRNA molecules. Mutations have been found in this gene in some patients with Alpers syndrome. [provided by RefSeq, Mar 2015]

Research Articles on PARS2

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Product Notes

The PARS2 pars2 (Catalog #AAA1395611) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 30-475, Full length protein. The amino acid sequence is listed below: HHCAPRRGRR LLLSRVFQPQ NLREDRVLSL QDKSDDLTCK SQRLMLQVGL IYPASPGCYH LLPYTVRAME KLVRVIDQEM QAIGGQKVNM PSLSPAELWQ ATNRWDLMGK ELLRLRDRHG KEYCLGPTHE EAITALIASQ KKLSYKQLPF LLYQVTRKFR DEPRPRFGLL RGREFYMKDM YTFDSSPEAA QQTYSLVCDA YCSLFNKLGL PFVKVQADVG TIGGTVSHEF QLPVDIGEDR LAICPRCSFS ANMETLDLSQ MNCPACQGPL TKTKGIEVGH TFYLGTKYSS IFNAQFTNVC GKPTLAEMGC YGLGVTRILA AAIEVLSTED CVRWPSLLAP YQACLIPPKK GSKEQAASEL IGQLYDHITE AVPQLHGEVL LDDRTHLTIG NRLKDANKFG YPFVIIAGKR ALEDPAHFEV WCQNTGEVAF LTKDGVMDLL TPVQTV. It is sometimes possible for the material contained within the vial of "Probable proline--tRNA ligase, mitochondrial (PARS2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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