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Rat poly (ADP-ribose) polymerase 1 ELISA Kit | PARP1 elisa kit

Rat Poly [ADP-ribose] polymerase 1, PARP1 ELISA Kit

Gene Names
Parp1; ARTD1; Adprt; Parp-1
Reactivity
Rat
Synonyms
poly (ADP-ribose) polymerase 1; Rat Poly [ADP-ribose] polymerase 1; PARP1 ELISA Kit; Rat Poly [ADP-ribose] polymerase 1 (PARP1) ELISA kit; RP11-125A15.2; ADPRT; ADPRT1; PARP; PARP-1; PPOL; pADPRT-1; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) ; ADP-ribosyltransferase NAD (+) ; poly (ADP-ribose) polymerase family; member 1; po; PARP1 elisa kit
Ordering
 
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For Research Use Only!
Reactivity
Rat
Preparation and Storage
Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
112,660 Da
NCBI Official Full Name
poly
NCBI Official Synonym Full Names
poly (ADP-ribose) polymerase 1
NCBI Official Symbol
Parp1
NCBI Official Synonym Symbols
ARTD1; Adprt; Parp-1
NCBI Protein Information
poly [ADP-ribose] polymerase 1; poly [ADP-ribose] polymerase 1; ADPRT 1; ADP-ribosyltransferase 1; poly[ADP-ribose] synthase 1; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase); poly[ADP-ribose] synthetase 1; NAD(+) ADP-ribosyltransferase 1; poly(ADP-ribose) polymerase PARP-1; poly (ADP-ribose) polymerase family, member 1; ADP-ribosyltransferase diphtheria toxin-like 1; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)
UniProt Protein Name
Poly [ADP-ribose] polymerase 1
UniProt Gene Name
Parp1
UniProt Synonym Gene Names
Adprt; PARP-1; ARTD1; ADPRT 1
UniProt Entry Name
PARP1_RAT

NCBI Description

catalyzes poly (ADP-ribose) protein modification; plays a role in DNA repair and genome stability [RGD, Feb 2006]

Uniprot Description

PARP1: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. Mediates the poly(ADP- ribosyl)ation of APLF and CHFR. Positively regulates the transcription of MTUS1 and negatively regulates the transcription of MTUS2/TIP150. With EEF1A1 and TXK, forms a complex that acts as a T-helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production. Component of a base excision repair (BER) complex, containing at least XRCC1, PARP2, POLB and LRIG3. Homo- and heterodimer with PARP2. Interacts with PARP3, APTX and SRY. The SWAP complex consists of NPM1, NCL, PARP1 and SWAP70. Interacts with TIAM2 and ZNF423. Interacts (when poly-ADP- ribosylated) with CHD1L. Interacts with the DNA polymerase alpha catalytic subunit POLA1; this interaction functions as part of the control of replication fork progression. Interacts with EEF1A1, RNF4 and TXK.

Protein type: Transferase; Nucleolus; Nuclear envelope; DNA repair, damage; Nuclear receptor co-regulator; EC 2.4.2.30

Cellular Component: nucleoplasm; transcription factor complex; protein complex; membrane; cytoplasm; nucleolus; nuclear envelope; nucleus

Molecular Function: identical protein binding; enzyme binding; DNA binding; zinc ion binding; transferase activity, transferring pentosyl groups; protein N-terminus binding; protein kinase binding; transcription factor binding; NAD binding; NAD+ ADP-ribosyltransferase activity

Biological Process: protein autoprocessing; protein amino acid ADP-ribosylation; transcription, DNA-dependent; cellular response to insulin stimulus; base-excision repair; transforming growth factor beta receptor signaling pathway; double-strand break repair; positive regulation of transcription from RNA polymerase II promoter; DNA damage response, detection of DNA damage; regulation of growth rate; DNA metabolic process; telomere maintenance

Research Articles on PARP1

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Product Notes

The Rat PARP1 parp1 (Catalog #AAA9320155) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9320155 ELISA Kit recognizes Rat PARP1. It is sometimes possible for the material contained within the vial of "poly (ADP-ribose) polymerase 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.
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