Proteasome-activating nucleotidase (pan) Recombinant Protein | pan recombinant protein
Recombinant Methanothermobacter thermautotrophicus Proteasome-activating nucleotidase (pan)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Proteasome-activating nucleotidase (pan); Recombinant Methanothermobacter thermautotrophicus Proteasome-activating nucleotidase (pan); Proteasome-activating nucleotidase; PAN; Proteasomal ATPase; Proteasome regulatory ATPase; Proteasome regulatory particle; pan recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-410aa; full length protein
Sequence
MENNSQNVLK KIEDLKKEVR MLKEENSKTK RNLMWKIRKL EKDKLLIENE RTRLDREVKSLRGEIERFRT PPLVIATVTE VLDDHRVAVK STTGPHFVIN YSRFIDRKQL EPGARVALNQQTFSIVDVLP SEKDPVVTGM EVEEKPDVSY EQIGGLEEQV REVKETVELP LKKPELFEKIGIEPPKGVLL YGPPGTGKTL LAKAVAHETN ATFIKIVASE FVRKYIGEGA RLVRGVFELAKEKSPSIIFI DEIDAVAAKR LKSSTSGDRE VQRTLMQLLA ELDGFESRGN VGIVAATNRPDILDPALLRP GRFDRFIEVP LPNEDGRREI LKIHTSGMAL AEEVDIELLA RITDGASGADLKAICTEAGM FAIRDERDEV TMADFMDAVD KIMGVEKEEE YKQETGVMFG
Sequence Length
410
Species
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
46,111 Da
NCBI Official Full Name
proteasome-activating nucleotidase
NCBI Official Symbol
MTH728
NCBI Protein Information
proteasome-activating nucleotidase
UniProt Protein Name
Proteasome-activating nucleotidase
Protein Family
UniProt Gene Name
pan
UniProt Synonym Gene Names
PAN
UniProt Entry Name
PAN_METTH
Uniprot Description
ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
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Product Notes
The pan pan (Catalog #AAA1070156) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-410aa; full length protein. The amino acid sequence is listed below: MENNSQNVLK KIEDLKKEVR MLKEENSKTK RNLMWKIRKL EKDKLLIENE RTRLDREVKS LRGEIERFRT PPLVIATVTE VLDDHRVAVK STTGPHFVIN YSRFIDRKQL EPGARVALNQ QTFSIVDVLP SEKDPVVTGM EVEEKPDVSY EQIGGLEEQV REVKETVELP LKKPELFEKI GIEPPKGVLL YGPPGTGKTL LAKAVAHETN ATFIKIVASE FVRKYIGEGA RLVRGVFELA KEKSPSIIFI DEIDAVAAKR LKSSTSGDRE VQRTLMQLLA ELDGFESRGN VGIVAATNRP DILDPALLRP GRFDRFIEVP LPNEDGRREI LKIHTSGMAL AEEVDIELLA RITDGASGAD LKAICTEAGM FAIRDERDEV TMADFMDAVD KIMGVEKEEE YKQETGVMFG. It is sometimes possible for the material contained within the vial of "Proteasome-activating nucleotidase (pan), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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