p21-activated protein kinase-interacting protein 1 (Pak1ip1) Recombinant Protein | Pak1ip1 recombinant protein
Recombinant Mouse p21-activated protein kinase-interacting protein 1 (Pak1ip1)
NCBI and Uniprot Product Information
Uniprot Description
Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which has been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42. May be involved in ribosomal large subunit assembly.
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Product Notes
The Pak1ip1 pak1ip1 (Catalog #AAA1465248) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-382, full length protein. The amino acid sequence is listed below: MELVAGSYEQ VLFGFTVQRG PAKSGHQETW TPVADFTHHS HTASLSVLAS NSRYVVSGSK DETIHIYDMK RKVEHGALVH HAGTVTCLKF HGNQHLISGA EDGHICIWDV KRWKCLKTFK AHRGHVTFLS IHPSGKLALS VGTDKTLRTW NLIEGRSAFI KNIKENAHIV EWSPSGGKYI VVVQNKVDVY RLGTASVSGT ITNGKRISSV TFLSDSVLAV AGDEEVVRIF DCDSLECLCE FRAHENRVKD MVSFEVPDHH VLVTASNDGF IKMWTLPQDK KVPPSLLCEA KTGARLTCLT VWLDRAANGM ASLPPAAEPC PDQPKTIEKE SGDTVQEETS EPNSEKSDVS GDSKQPTKGN SPVTAKKRKM ATMSEKKRKK KM. It is sometimes possible for the material contained within the vial of "p21-activated protein kinase-interacting protein 1 (Pak1ip1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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