Polyadenylate-binding protein 2 (Pabp2) Recombinant Protein | Pabp2 recombinant protein

Recombinant Drosophila melanogaster Polyadenylate-binding protein 2 (Pabp2)

Cat. Num. AAA1297782

• Gene Names: Pabp2; CG2163; DmelCG2163; dpabII; pabp2; pAbp2; PABP2; PABPN1; rox2; Rox2; ROX2
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Polyadenylate-binding protein 2 (Pabp2); Recombinant Drosophila melanogaster Polyadenylate-binding protein 2 (Pabp2); Pabp2 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-224, Full length protein
• Sequence: MADEDITLNEDQLLESLEETNGEQETEIATEVEEEGSMQIDPELEAIKARVKEMEEEAEKIKQMQSEVDKQMAGGSTTGLATVPLSLEEKQEIDTRSVYVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYIEFGSKEFVETALAMNETLFRGRQIKVMSKRTNRPGLSTTNRFARGSFRGRGARVSRACCHSTFRGARRAMGYRGRANYYAPY
• Sequence Length: 224

• Species: Drosophila melanogaster (Fruit fly)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 17136784
• NCBI GeneID: 35788
• NCBI Accession #: NP_476902.1
• NCBI GenBank Nucleotide #: NM_057554.4
• UniProt Accession #: Q7KNF2; Q27926; Q7JQ60; A1Z7B1
• Molecular Weight: 24,978 Da
• NCBI Official Full Name: Pabp2, isoform A
• NCBI Official Symbol: Pabp2
• NCBI Official Synonym Symbols: CG2163; DmelCG2163; dpabII; pabp2; pAbp2; PABP2; PABPN1; rox2; Rox2; ROX2
• NCBI Protein Information: CG2163 gene product from transcript CG2163-RA
• UniProt Protein Name: Polyadenylate-binding protein 2
• UniProt Gene Name: Pabp2
• UniProt Synonym Gene Names: PABP-2; Poly(A)-binding protein 2; dPABP2; PABII

Uniprot Description

Involved in the 3'-end formation of mRNA precursors (pre-mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product (PubMed:10481015). Stimulates poly(A) polymerase (PAPOLA) conferring processivity on the poly(A) tail elongation reaction and controls also the poly(A) tail length (). Increases the affinity of poly(A) polymerase for RNA (). Binds to poly(A) and to poly(G) with high affinity (PubMed:10481015). May protect the poly(A) tail from degradation (). Plays a role in the positive regulation of alpha-1,3 fucosylation, possibly by cooperating with swm which regulates nuclear export of fucosyltransferase FucTA (PubMed:21203496).