Prolyl 4-hydroxylase subunit alpha-1 (P4ha1) Recombinant Protein | P4ha1 recombinant protein
Recombinant Mouse Prolyl 4-hydroxylase subunit alpha-1 (P4ha1)
Gene Names
P4ha1; P4ha; AL022634
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Prolyl 4-hydroxylase subunit alpha-1 (P4ha1); Recombinant Mouse Prolyl 4-hydroxylase subunit alpha-1 (P4ha1); P4ha1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
18-534, Full length protein
Sequence
HPGFFTSIGQMTDLIHNEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLILKDMSDGFISNLTIQRQYFPNDEDQVGAAKALFRLQDTYNLDTNTISKGNLPGVQHKSFLTAEDCFELGKVAYTEADYYHTELWMEQALTQLEEGELSTVDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQRANGNLVYFEYIMSKEKDANKSASGDQSDQKTAPKKKGIAVDYLPERQKYEMLCRGEGIKMTPRRQKRLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRLRRATISNPVTGALETVHYRISKSAWLSGYEDPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFRELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE
Sequence Length
517
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for P4ha1 recombinant protein
This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
60,886 Da
NCBI Official Full Name
prolyl 4-hydroxylase subunit alpha-1 isoform 2
NCBI Official Synonym Full Names
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide
NCBI Official Symbol
P4ha1
NCBI Official Synonym Symbols
P4ha; AL022634
NCBI Protein Information
prolyl 4-hydroxylase subunit alpha-1
UniProt Protein Name
Prolyl 4-hydroxylase subunit alpha-1
Protein Family
UniProt Gene Name
P4ha1
UniProt Synonym Gene Names
4-PH alpha-1
Uniprot Description
Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
Research Articles on P4ha1
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Product Notes
The P4ha1 p4ha1 (Catalog #AAA1447786) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 18-534, Full length protein. The amino acid sequence is listed below: HPGFFTSIGQ MTDLIHNEKD LVTSLKDYIK AEEDKLEQIK KWAEKLDRLT STATKDPEGF VGHPVNAFKL MKRLNTEWSE LENLILKDMS DGFISNLTIQ RQYFPNDEDQ VGAAKALFRL QDTYNLDTNT ISKGNLPGVQ HKSFLTAEDC FELGKVAYTE ADYYHTELWM EQALTQLEEG ELSTVDKVSV LDYLSYAVYQ QGDLDKALLL TKKLLELDPE HQRANGNLVY FEYIMSKEKD ANKSASGDQS DQKTAPKKKG IAVDYLPERQ KYEMLCRGEG IKMTPRRQKR LFCRYHDGNR NPKFILAPAK QEDEWDKPRI IRFHDIISDA EIEIVKDLAK PRLRRATISN PVTGALETVH YRISKSAWLS GYEDPVVSRI NMRIQDLTGL DVSTAEELQV ANYGVGGQYE PHFDFARKDE PDAFRELGTG NRIATWLFYM SDVSAGGATV FPEVGASVWP KKGTAVFWYN LFASGEGDYS TRHAACPVLV GNKWVSNKWL HERGQEFRRP CTLSELE. It is sometimes possible for the material contained within the vial of "Prolyl 4-hydroxylase subunit alpha-1 (P4ha1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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