Outer capsid glycoprotein VP7 Recombinant Protein
Recombinant Rotavirus A Outer capsid glycoprotein VP7
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Outer capsid glycoprotein VP7; Recombinant Rotavirus A Outer capsid glycoprotein VP7; Outer capsid glycoprotein VP7 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
51-326, Full length protein
Sequence
QNYGLNLPITGSMDAVYTNSTQEEVFLTSTLCLYYPTEASTQINDGDWKDSLSQMFLTKGWPTGSVYFKEYSNIVDFSVDPQLYCDYNLVLMKYDQSLELDMSELADLILNEWLCNPMDVTLYYYQQSGESNKWISMGSSCTVKVCPLNTQTLGIGCQTTNVDSFEMIAENEKLAIVDVVDGINHKINLTTTTCTIRNCKKLGPRENVAVIQVGGSNVLDITADPTTNPQTERMMRVNWKKWWQVFYTIVDYINQIVQVMSKRSRSLNSAAFYYRV
Sequence Length
276
Species
Rotavirus A (strain Human/United States/Wa/1974 G1-P1A[8]-I1-R1-C1-M1-A1-N1-T1-E1-H1) (RV-A)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
UniProt Accession #
Molecular Weight
33,941 Da
NCBI Official Full Name
Outer capsid glycoprotein VP7
UniProt Protein Name
Outer capsid glycoprotein VP7
Protein Family
Uniprot Description
Outer capsid protein involved in attachment and possibly entry into the host epithelial cell. It is subsequently lost, together with VP4, following virus entry into the host cell. The outer layer contains 780 copies of VP7, grouped as 260 trimers. Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors. In integrin-dependent strains, VP7 seems to essentially target the integrin heterodimers ITGAX/ITGB2 and ITGA5/ITGB3 at a postbinding stage, once the initial attachment by VP4 has been achieved ().
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Product Notes
The Outer capsid glycoprotein VP7 (Catalog #AAA1022812) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 51-326, Full length protein. The amino acid sequence is listed below: QNYGLNLPIT GSMDAVYTNS TQEEVFLTST LCLYYPTEAS TQINDGDWKD SLSQMFLTKG WPTGSVYFKE YSNIVDFSVD PQLYCDYNLV LMKYDQSLEL DMSELADLIL NEWLCNPMDV TLYYYQQSGE SNKWISMGSS CTVKVCPLNT QTLGIGCQTT NVDSFEMIAE NEKLAIVDVV DGINHKINLT TTTCTIRNCK KLGPRENVAV IQVGGSNVLD ITADPTTNPQ TERMMRVNWK KWWQVFYTIV DYINQIVQVM SKRSRSLNSA AFYYRV. It is sometimes possible for the material contained within the vial of "Outer capsid glycoprotein VP7, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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