Outer dense fiber protein 2 (Odf2) Recombinant Protein | Odf2 recombinant protein

Recombinant Rat Outer dense fiber protein 2 (Odf2) , partial

• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Outer dense fiber protein 2 (Odf2); Recombinant Rat Outer dense fiber protein 2 (Odf2); partial; Odf2 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 705

• Species: Rat
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for Odf2 recombinant protein

The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. This gene encodes one of the major outer dense fiber proteins. Multiple protein isoforms are encoded by transcript variants of this gene; however, not all isoforms and variants have been fully described.

NCBI and Uniprot Product Information

• NCBI GI #: 222418641
• NCBI GeneID: 29479
• NCBI Accession #: NP_001138477.1
• NCBI GenBank Nucleotide #: NM_001145005.1
• UniProt Accession #: Q6AYX5; O70408; P97575; Q62693; Q9JIZ3
• Molecular Weight: 71,315 Da
• NCBI Official Full Name: outer dense fiber protein 2 isoform 1
• NCBI Official Synonym Full Names: outer dense fiber of sperm tails 2
• NCBI Official Symbol: Odf2
• NCBI Protein Information: outer dense fiber protein 2
• UniProt Protein Name: Outer dense fiber protein 2
• Protein Family: Outer dense fiber protein
• UniProt Gene Name: Odf2
• UniProt Synonym Gene Names: Odf84

NCBI Description

localized to both the cortex and medulla of outer dense fibers, specialized cytoskeletal components of the sperm tail; may interact with other outer dense fiber proteins via a leucine zipper [RGD, Feb 2006]

Uniprot Description

Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes. Required for the formation and/or maintenance of normal CETN1 assembly.