GP210 Blocking Peptide | NUP210 blocking peptide

GP210 Blocking Peptide

Cat. Num. AAA9622239

• Gene Names: NUP210; GP210; POM210
• Applications: Blocking/Control
• Purity: The purity is >90%,tested by HPLC and MS.
• Synonyms: GP210; GP210 Blocking Peptide; FLJ22389; GP 210; KIAA0906; Nuclear envelope pore membrane protein POM 210; Nuclear pore membrane glycoprotein 210; Nuclear pore protein gp210; Nucleoporin 210; Nucleoporin 210kDa; Nucleoporin Nup210; Nucleoporin210; NUP 210; Nup210; PO210_HUMAN; POM 210; POM210; Pore membrane protein of 210 kDa; NUP210 blocking peptide

• Purity/Purification: The purity is >90%,tested by HPLC and MS.
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

• Applicable Applications for NUP210 blocking peptide: Blocking/Control
• Notes: For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for NUP210 blocking peptide

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (immunoblot) and immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or immunostaining performed with the neutralized antibody.

NCBI and Uniprot Product Information

• NCBI GI #: 27477134
• NCBI GeneID: 23225
• NCBI Accession #: NP_079199.2
• NCBI GenBank Nucleotide #: NP_079199.2
• UniProt Accession #: Q8TEM1; O94980; Q6NXG6; Q8NBJ1; Q9H6C8; Q9UFP3; A6NN56
• Molecular Weight: 105,810 Da
• NCBI Official Full Name: nuclear pore membrane glycoprotein 210
• NCBI Official Synonym Full Names: nucleoporin 210kDa
• NCBI Official Symbol: NUP210
• NCBI Official Synonym Symbols: GP210; POM210
• NCBI Protein Information: nuclear pore membrane glycoprotein 210; nuclear envelope pore membrane protein POM 210; nuclear pore protein gp210; nucleoporin Nup210; pore membrane protein of 210 kDa
• UniProt Protein Name: Nuclear pore membrane glycoprotein 210
• Protein Family: Nuclear pore membrane glycoprotein
• UniProt Gene Name: NUP210
• UniProt Synonym Gene Names: KIAA0906; Nuclear pore protein gp210; POM210
• UniProt Entry Name: PO210_HUMAN

NCBI Description

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a membrane-spanning glycoprotein that is a major component of the nuclear pore complex. Multiple pseudogenes related to this gene are located on chromosome 3. [provided by RefSeq, Jul 2013]

Uniprot Description

NUP210: Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity. Belongs to the NUP210 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Nucleoporin; Membrane protein, integral

Chromosomal Location of Human Ortholog: 3p25.1

Cellular Component: endoplasmic reticulum membrane; nuclear membrane; membrane; nuclear envelope; nuclear pore

Molecular Function: protein dimerization activity

Biological Process: mRNA transport; viral reproduction; cytokine and chemokine mediated signaling pathway; mitotic nuclear envelope disassembly; pathogenesis; glucose transport; viral infectious cycle; protein transport; hexose transport; carbohydrate metabolic process; viral transcription; gene expression; mitotic cell cycle; transmembrane transport