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SDS-Page

Neurotensin Recombinant Protein | NTS recombinant protein

Neurotensin Protein, Human, Recombinant (hFc Tag)

Gene Names
NTS; NN; NT; NT/N; NTS1; NMN-125
Purity
>85% as determined by SDS-PAGE
Synonyms
Neurotensin; Neurotensin Protein; Human; Recombinant (hFc Tag); Human Neurotensin Protein (Fc Tag); NMN-125 Protein; NN Protein; NT Protein; NT/N Protein; NTS1 Protein; neurotensin; NTS recombinant protein
Ordering
For Research Use Only!
Host
HEK293 Cells
Purity/Purification
>85% as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Sequence
Met1-Leu148
Species
Human
Endotoxin
<1.0EU per ug protein as determined by the LAL method.
Predicted N Terminal
Ser 24
Tag
C-human IgG1-Fc
Protein Construction
A DNA sequence encoding the human NTS (NP_006174.1)(Met1-Leu148) was expressed with the Fc region of human IgG1 at the C-terminus.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.

SDS-Page

SDS-Page
Related Product Information for NTS recombinant protein
Background: NTS (Neurotensin) is a Protein Coding gene. This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. NTS is a neuropeptide distributed in the central nervous and digestive systems. It belongs to the neurotensin family. NTS is an endogenous tridecapeptide of the central nervous system and the gastrointestinal tract of different mammalian species including the human. The human gene encoding neurotensin has previously been assigned to chromosome 12 but no regional localization was available. NTS is widely expressed in the central and peripheral nervous system, which is mainly mediated by neurotensin receptor1 (NTSR1) to activate the related downstream signaling pathways. Diseases associated with NTS include Dumping Syndrome and Duodenogastric Reflux.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
19,795 Da
NCBI Official Full Name
neurotensin/neuromedin N preproprotein
NCBI Official Synonym Full Names
neurotensin
NCBI Official Symbol
NTS
NCBI Official Synonym Symbols
NN; NT; NT/N; NTS1; NMN-125
NCBI Protein Information
neurotensin/neuromedin N; pro-neurotensin/neuromedin
UniProt Protein Name
Neurotensin/neuromedin N
Protein Family
UniProt Gene Name
NTS
UniProt Synonym Gene Names
NN; NmN; NT
UniProt Entry Name
NEUT_HUMAN

NCBI Description

This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active. [provided by RefSeq, Jul 2008]

Uniprot Description

NTS: Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle. Belongs to the neurotensin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 12q21

Cellular Component: transport vesicle; extracellular region

Molecular Function: neuropeptide hormone activity; protein binding

Biological Process: signal transduction; regulation of blood vessel size

Research Articles on NTS

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Product Notes

The NTS nts (Catalog #AAA8121879) is a Recombinant Protein produced from HEK293 Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Met1-Leu14 8. It is sometimes possible for the material contained within the vial of "Neurotensin, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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