High affinity nerve growth factor receptor Recombinant Protein | Ntrk1 recombinant protein
High affinity nerve growth factor receptor
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
NCBI and Uniprot Product Information
NCBI Description
a protooncogene; receptor that binds to nerve growth factor (NGF) [RGD, Feb 2006]
Uniprot Description
TrkA: a receptor tyrosine kinase of the Trk family. High affinity receptor for nerve growth factor, neurotrophin-3 and neurotrophin-4/5 but not brain- derived neurotrophic factor. Known substrates include Shc, PI-3K, and PLC-gamma-1. Has a crucial role in the development and function of the nociceptive reception system. Two splice variant isoforms have been described.
Protein type: EC 2.7.10.1; Kinase, protein; Protein kinase, tyrosine (receptor); Oncoprotein; Membrane protein, integral; Protein kinase, TK; TK group; Trk family
Cellular Component: axon; cell soma; cell surface; cytoplasm; cytoplasmic vesicle; dendrite; early endosome; Golgi membrane; integral to plasma membrane; late endosome; plasma membrane; protein complex; receptor complex
Molecular Function: GPI-linked ephrin receptor activity; kinase binding; nerve growth factor binding; nerve growth factor receptor activity; neurotrophin p75 receptor binding; protein binding; protein homodimerization activity; protein-tyrosine kinase activity; transmembrane receptor protein serine/threonine kinase activity; transmembrane receptor protein tyrosine kinase activity
Biological Process: activation of MAPKK activity; activation of NF-kappaB transcription factor; adenylate cyclase activation; aging; axon guidance; B cell differentiation; detection of mechanical stimulus involved in sensory perception of pain; detection of temperature stimulus involved in sensory perception of pain; learning and/or memory; mechanoreceptor differentiation; negative regulation of cell proliferation; negative regulation of neuron apoptosis; nerve growth factor receptor signaling pathway; nervous system development; olfactory nerve development; phospholipase C activation; positive regulation of angiogenesis; positive regulation of GTPase activity; positive regulation of programmed cell death; positive regulation of protein amino acid phosphorylation; positive regulation of Ras protein signal transduction; positive regulation of synaptic transmission, glutamatergic; positive regulation of synaptogenesis; protein amino acid autophosphorylation; protein amino acid phosphorylation; Ras protein signal transduction; response to activity; response to axon injury; response to drug; response to electrical stimulus; response to ethanol; response to hydrostatic pressure; response to nicotine; response to nutrient levels; response to radiation; sensory perception of pain; Sertoli cell development; small GTPase mediated signal transduction; sympathetic nervous system development
Research Articles on Ntrk1
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Product Notes
The Ntrk1 ntrk1 (Catalog #AAA7043167) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 33-799aa; full length protein. The amino acid sequence is listed below: AASCRETCCP VGPSGLRCTR AGTLNTLRGL RGAGNLTELY VENQRDLQRL EFEDLQGLGE LRSLTIVKSG LRFVAPDAFH FTPRLSHLNL SSNALESLSW KTVQGLSLQD LTLSGNPLHC SCALLWLQRW EQEDLCGVYT QKLQGSGSGD QFLPLGHNNS CGVPSVKIQM PNDSVEVGDD VFLQCQVEGQ ALQQADWILT ELEGTATMKK SGDLPSLGLT LVNVTSDLNK KNVTCWAEND VGRAEVSVQV SVSFPASVHL GKAVEQHHWC IPFSVDGQPA PSLRWFFNGS VLNETSFIFT QFLESALTNE TMRHGCLRLN QPTHVNNGNY TLLAANPYGQ AAASIMAAFM DNPFEFNPED PIPVSFSPVD TNSTSRDPVE KKDETPFGVS VAVGLAVSAA LFLSALLLVL NKCGQRSKFG INRPAVLAPE DGLAMSLHFM TLGGSSLSPT EGKGSGLQGH IMENPQYFSD TCVHHIKRQD IILKWELGEG AFGKVFLAEC YNLLNDQDKM LVAVKALKET SENARQDFHR EAELLTMLQH QHIVRFFGVC TEGGPLLMVF EYMRHGDLNR FLRSHGPDAK LLAGGEDVAP GPLGLGQLLA VASQVAAGMV YLASLHFVHR DLATRNCLVG QGLVVKIGDF GMSRDIYSTD YYRVGGRTML PIRWMPPESI LYRKFSTESD VWSFGVVLWE IFTYGKQPWY QLSNTEAIEC ITQGRELERP RACPPDVYAI MRGCWQREPQ QRLSMKDVHA RLQALAQAPP SYLDVLG. It is sometimes possible for the material contained within the vial of "High affinity nerve growth factor receptor, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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