Alpha N-terminal protein methyltransferase 1A (METTL11A) Recombinant Protein | METTL11A recombinant protein
Recombinant Ailuropoda melanoleuca Alpha N-terminal protein methyltransferase 1A (METTL11A)
Gene Names
NTMT1; NTM1A; METTL11A
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Alpha N-terminal protein methyltransferase 1A (METTL11A); Recombinant Ailuropoda melanoleuca Alpha N-terminal protein methyltransferase 1A (METTL11A); METTL11A recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-223, Full length protein
Sequence
MTSEVIEDEKQFYLKAKTYWKEVPPTVDGMLGGYGHISSIDISSSRKFLQRFLREGPNKTGTSCALDCGAGIGRITKRLLLPLFGVVDMVDVTEDFLIKARTYLGEEGKRVRNYFCCGLQDFSPEPNSYDVIWIQWVIGHLTDQHLAEFLRRCKQGLRPNGIIVIKDNMAQEGVILDDVDSSVCRDLDVVHRIVRSAGLSLLAEERQENLPDEIYHVYSLALR
Sequence Length
223
Species
Ailuropoda melanoleuca (Giant panda)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
25,284 Da
NCBI Official Full Name
N-terminal Xaa-Pro-Lys N-methyltransferase 1 isoform X1
NCBI Official Symbol
NTMT1
NCBI Official Synonym Symbols
NTM1A; METTL11A
NCBI Protein Information
N-terminal Xaa-Pro-Lys N-methyltransferase 1
UniProt Protein Name
N-terminal Xaa-Pro-Lys N-methyltransferase 1
UniProt Gene Name
NTMT1
UniProt Synonym Gene Names
METTL11A; NTM1A
Uniprot Description
Distributive alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Gly/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of the exposed alpha-amino group of the Ala, Gly or Ser residue in the [Ala/Gly/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Some of the substrates may be primed by METTL11B-mediated monomethylation. Catalyzes the trimethylation of the N-terminal Gly in CENPA (after removal of Met-1). Responsible for the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on RCC1.
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Product Notes
The METTL11A ntmt1 (Catalog #AAA1049104) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-223, Full length protein. The amino acid sequence is listed below: MTSEVIEDEK QFYLKAKTYW KEVPPTVDGM LGGYGHISSI DISSSRKFLQ RFLREGPNKT GTSCALDCGA GIGRITKRLL LPLFGVVDMV DVTEDFLIKA RTYLGEEGKR VRNYFCCGLQ DFSPEPNSYD VIWIQWVIGH LTDQHLAEFL RRCKQGLRPN GIIVIKDNMA QEGVILDDVD SSVCRDLDVV HRIVRSAGLS LLAEERQENL PDEIYHVYSL ALR. It is sometimes possible for the material contained within the vial of "Alpha N-terminal protein methyltransferase 1A (METTL11A), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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