Neuron-specific protein family member 1 (Nsg1) Recombinant Protein | Nsg1 recombinant protein

Recombinant Rat Neuron-specific protein family member 1 (Nsg1), partial

Cat. Num. AAA1051897

• Gene Names: Nsg1; PEP1; Bsmrb; Neep21
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Neuron-specific protein family member 1 (Nsg1); Recombinant Rat Neuron-specific protein family member 1 (Nsg1); partial; Nsg1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-82
• Sequence: MVKLGNNFAE KGTKQPLLED GFDTIPLMTP LDVNQLQFPP PDKVVVKTKT EYEPDRKKGK ARPPKIAEFT VSITEGVTER FK
• Sequence Length: 82

• Species: Rat
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 47059500
• NCBI GeneID: 25247
• NCBI Accession #: NP_077042.2
• NCBI GenBank Nucleotide #: NM_024128.3
• UniProt Accession #: P02683; P02684; Q6P9Y0
• Molecular Weight: 20,943 Da
• NCBI Official Full Name: neuronal vesicle trafficking-associated protein 1
• NCBI Official Synonym Full Names: neuronal vesicle trafficking associated 1
• NCBI Official Symbol: Nsg1
• NCBI Official Synonym Symbols: PEP1; Bsmrb; Neep21
• NCBI Protein Information: neuronal vesicle trafficking-associated protein 1
• UniProt Protein Name: Neuronal vesicle trafficking-associated protein 1
• Protein Family: Neuron-specific protein family
• UniProt Gene Name: Nsg1

NCBI Description

(brain-specific protein that) may be involved in neuronal fiber networks [RGD, Feb 2006]

Uniprot Description

Plays a role in the recycling mechanism in neurons of multiple receptors, including AMPAR, APP and L1CAM and acts at the level of early endosomes to promote sorting of receptors toward a recycling pathway (PubMed:18299352, PubMed:15911354). Regulates sorting and recycling of GRIA2 through interaction with GRIP1 and then contributes to the regulation of synaptic transmission and plasticity by affecting the recycling and targeting of AMPA receptors to the synapse (PubMed:15911354). Is required for faithful sorting of L1CAM to axons by facilitating trafficking from somatodendritic early endosome or the recycling endosome (PubMed:18299352). In an other hand, induces apoptosis via the activation of CASP3 in response to DNA damage ().