DNA-directed RNA polymerase D subunit 1 (NRPD1) Recombinant Protein | NRPD1 recombinant protein

Recombinant Arabidopsis thaliana DNA-directed RNA polymerase D subunit 1 (NRPD1) , partial

• Gene Names: NRPD1A; F16P17.19; F16P17_19; NRPD1; NUCLEAR RNA POLYMERASE D 1A; nuclear RNA polymerase D1A; POL IVA; SDE4; SILENCING MOVEMENT DEFICIENT 2; SMD2
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: DNA-directed RNA polymerase D subunit 1 (NRPD1); Recombinant Arabidopsis thaliana DNA-directed RNA polymerase D subunit 1 (NRPD1); partial; NRPD1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 1453

• Species: Arabidopsis thaliana (Mouse-ear cress)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 334183598
• NCBI GeneID: 842605
• NCBI Accession #: NP_001185298.1
• NCBI GenBank Nucleotide #: NM_001198369.1
• UniProt Accession #: Q9LQ02
• Molecular Weight: 162,521 Da
• NCBI Official Full Name: nuclear RNA polymerase D1A
• NCBI Official Symbol: NRPD1A
• NCBI Official Synonym Symbols: F16P17.19; F16P17_19; NRPD1; NUCLEAR RNA POLYMERASE D 1A; nuclear RNA polymerase D1A; POL IVA; SDE4; SILENCING MOVEMENT DEFICIENT 2; SMD2
• NCBI Protein Information: nuclear RNA polymerase D1A
• UniProt Protein Name: DNA-directed RNA polymerase IV subunit 1
• Protein Family: DNA-directed RNA polymerase
• UniProt Gene Name: NRPD1
• UniProt Synonym Gene Names: NRPD1a; RMD3; RPD1; SDE4; SMD2; AtNRPD1a; Nuclear RNA polymerase D 1a; POL IV 1a

NCBI Description

Encodes one of two alternative largest subunits of a putative plant-specific RNA polymerase IV (aka RNA polymerase D). Required for posttranscriptional gene silencing.

Uniprot Description

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (). Largest and catalytic component of RNA polymerase IV which mediates 24-nt short-interfering RNAs (siRNA) accumulation. Implicated in siRNA-directed heterochromatin formation through the action of DCL3 and AGO4, and subsequent DNA methylation-dependent silencing of targeted sequences. Essential component of a self-reinforcing loop coupling de novo DNA methylation to siRNA production. Required for intercellular but not intracellular RNA interference (RNAi) leading to systemic post-transcriptional gene silencing. Involved in the maintenance of post-transcriptional RNA silencing.