Rat Nuclear Factor Erythroid 2-Related Factor 2 ELISA Kit | NRF2 elisa kit

Rat Nuclear Factor Erythroid 2-Related Factor 2 ELISA Kit

Cat. Num. AAA12148

• Gene Names: NFE2L2; NRF2
• Reactivity: Rat
• Synonyms: Nuclear Factor Erythroid 2-Related Factor 2; Rat Nuclear Factor Erythroid 2-Related Factor 2 ELISA Kit; NRF2 elisa kit

• Reactivity: Rat

• Assay Type: Quantitative Sandwich
• Detection Range: 62.5pg/ml-2000pg/ml
• Sensitivity: 10pg/ml
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for NRF2 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used for determine the level of ER (hereafter termed "analyte") in undiluted original Porcine serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 20149576
• NCBI GeneID: 4780
• NCBI Accession #: NP_006155.2
• NCBI GenBank Nucleotide #: NM_006164.4
• UniProt Accession #: Q16236; Q53RW6; Q59HH2; Q96F71; B2RBU2; B4E338; E9PGJ7
• Molecular Weight: 67,827 Da
• NCBI Official Full Name: nuclear factor erythroid 2-related factor 2 isoform 1
• NCBI Official Synonym Full Names: nuclear factor (erythroid-derived 2)-like 2
• NCBI Official Symbol: NFE2L2
• NCBI Official Synonym Symbols: NRF2
• NCBI Protein Information: nuclear factor erythroid 2-related factor 2; HEBP1; NFE2-related factor 2; NF-E2-related factor 2; nuclear factor erythroid-derived 2-like 2; nuclear factor, erythroid derived 2, like 2
• UniProt Protein Name: Nuclear factor erythroid 2-related factor 2
• Protein Family: Nuclear factor erythroid 2-related factor
• UniProt Gene Name: NFE2L2
• UniProt Synonym Gene Names: NRF2; NF-E2-related factor 2
• UniProt Entry Name: NF2L2_HUMAN

NCBI Description

This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Uniprot Description

NRF2: a transcription factor that regulates basal expression and antioxidant induction of a transcription factor for NAD(P)H:quinone oxidoreductase-1 (NQO1) and other detoxifying genes. Targeted for proteasomal degradation by INrf2. Oxidative stress causes its phosphorylation and release from INrf2.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 2q31

Cellular Component: nucleoplasm; centrosome; cytoplasm; plasma membrane; chromatin; nucleus; cytosol

Molecular Function: protein domain specific binding; protein binding; DNA binding; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; proteasomal ubiquitin-dependent protein catabolic process; positive regulation of blood coagulation; unfolded protein response; regulation of embryonic development; proteasomal ubiquitin-independent protein catabolic process; protein ubiquitination; positive regulation of transcription from RNA polymerase II promoter