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Atrial natriuretic peptide receptor 2 (NPR2) Recombinant Protein | NPR2 recombinant protein

Recombinant Bovine Atrial natriuretic peptide receptor 2 (NPR2), partial

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Atrial natriuretic peptide receptor 2 (NPR2); Recombinant Bovine Atrial natriuretic peptide receptor 2 (NPR2); partial; NPR2 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
17-458
Sequence
VRPP GARNLTLAVV LPEHNLSYAW AWPRVGPAVA LAMEALGRAL PVDLRFVSSE LDGACSEYLA PLRAVDLKLY HDPDLLLGPG CVYPAASVAR FASHWRLPLL TAGAVASGFS AKSEHYRTLV RTGPSAPKLG EFVVMLHGHF NWTARAALLY LDARTDDRPH YFTIEGVFEA LQGSNLSVQH QVYAREPGGP EQATHFIRAN GRIVYICGPL EMLHEILLQA QRENLTNGDY VFFYLDVFGE SLRAGPTRSM GRPWQDNRTR EQAQALREAF QTVLVITYRE PPNPEYQEFQ NRLLIRARED FGVELAPSLM NLIAGCFYDG ILLYAEVLNE TIQEGGTRED GLRIVEKMQG RRYRGVTGLV VMDKNNDRET DFVLWAMGDL VSGDFQPAAH YSGAEKQIWW TGRPIPWVKG VPPLDNPPCA FDMDDPSCDK TPLSTLAI
Sequence Length
442
Species
Bovine
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for NPR2 recombinant protein
This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
117,146 Da
NCBI Official Full Name
atrial natriuretic peptide receptor 2
NCBI Official Symbol
NPR2
NCBI Protein Information
atrial natriuretic peptide receptor 2
UniProt Protein Name
Atrial natriuretic peptide receptor 2
UniProt Gene Name
NPR2
UniProt Synonym Gene Names
ANP-B; ANPR-B; NPR-B; GC-B

Uniprot Description

Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth.

Research Articles on NPR2

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Product Notes

The NPR2 npr2 (Catalog #AAA966800) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 17-458. The amino acid sequence is listed below: VRPP GARNLTLAVV LPEHNLSYAW AWPRVGPAVA LAMEALGRAL PVDLRFVSSE LDGACSEYLA PLRAVDLKLY HDPDLLLGPG CVYPAASVAR FASHWRLPLL TAGAVASGFS AKSEHYRTLV RTGPSAPKLG EFVVMLHGHF NWTARAALLY LDARTDDRPH YFTIEGVFEA LQGSNLSVQH QVYAREPGGP EQATHFIRAN GRIVYICGPL EMLHEILLQA QRENLTNGDY VFFYLDVFGE SLRAGPTRSM GRPWQDNRTR EQAQALREAF QTVLVITYRE PPNPEYQEFQ NRLLIRARED FGVELAPSLM NLIAGCFYDG ILLYAEVLNE TIQEGGTRED GLRIVEKMQG RRYRGVTGLV VMDKNNDRET DFVLWAMGDL VSGDFQPAAH YSGAEKQIWW TGRPIPWVKG VPPLDNPPCA FDMDDPSCDK TPLSTLAI. It is sometimes possible for the material contained within the vial of "Atrial natriuretic peptide receptor 2 (NPR2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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