SDS-Page
ITGB1BP3 recombinant protein
ITGB1BP3, 1-230aa, Human, His tag, E Coli
Gene Names
NMRK2; MIBP; NRK2; ITGB1BP3
Applications
SDS-Page
Purity
> 90% by SDS-PAGE
Synonyms
ITGB1BP3; 1-230aa; Human; His tag; E Coli; Nicotinamide riboside kinase 2; MIBP; NRK2; ITGB1BP3 recombinant protein
Host
E Coli
Purity/Purification
> 90% by SDS-PAGE
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.1M NaCl, 40% glycerol, 1mM DTT
Concentration
0.25 mg/ml (determined by Bradford assay) (varies by lot)
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMKLIVGI GGMTNGGKTT LTNSLLRALP NCCVIHQDDF FKPQDQIAVG EDGFKQWDVL ESLDMEAMLD TVQAWLSSPQ KFARAHGVSV QPEASDTHIL LLEGFLLYSY KPLVDLYSRR YFLTVPYEEC KWRRSTRNYT VPDPPGLFDG HVWPMYQKYR QEMEANGVEV VYLDGMKSRE ELFREVLEDI QNSLLNRSQE SAPSPARPAR TQGPGRGCGH RTARPAASQQ DSM
Sequence Length
230
Applicable Applications for ITGB1BP3 recombinant protein
SDS-PAGE
Antigen Species
Human
Tag Information
His-tag
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
SDS-Page
SDS-Page
Related Product Information for ITGB1BP3 recombinant protein
Nicotinamide riboside kinase 2, also known as ITGB1BP3, belongs to the uridine kinase family and NRK subfamily. ITGB1BP3 is found at lower levels in heart and is downregulated during myoblast differentiation. ITGB1BP3 catalyzes the phosphorylation of nicotinic acid riboside and nicotinamide riboside to form nicotinic acid mononucleotide and nicotinamide mononucleotide. Recombinant human ITGB1BP3 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.
Product Categories/Family for ITGB1BP3 recombinant protein
References
Li J., et al. (1999) J Cell Biol. 147: 1391-1398; Li J., et al. (2003) Dev Biol. 261: 209-219.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
28.4 kDa (253aa), confirmed by MALDI-TOF
NCBI Official Full Name
nicotinamide riboside kinase 2 isoform 2
NCBI Official Synonym Full Names
nicotinamide riboside kinase 2
NCBI Official Symbol
NMRK2
NCBI Official Synonym Symbols
MIBP; NRK2; ITGB1BP3
NCBI Protein Information
nicotinamide riboside kinase 2
UniProt Protein Name
Nicotinamide riboside kinase 2
UniProt Gene Name
NMRK2
UniProt Synonym Gene Names
ITGB1BP3; NRK2; RNK 2
Uniprot Description
Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). Reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. Involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation. May play a role in the regulation of terminal myogenesis.
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Product Notes
The ITGB1BP3 nmrk2 (Catalog #AAA204773) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The tag for this protein is His-tag. AAA Biotech's ITGB1BP3 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the ITGB1BP3 nmrk2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSH MGSMKLIVGI GGMTNGGKTT LTNSLLRALP NCCVIHQDDF FKPQDQIAVG EDGFKQWDVL ESLDMEAMLD TVQAWLSSPQ KFARAHGVSV QPEASDTHIL LLEGFLLYSY KPLVDLYSRR YFLTVPYEEC KWRRSTRNYT VPDPPGLFDG HVWPMYQKYR QEMEANGVEV VYLDGMKSRE ELFREVLEDI QNSLLNRSQE SAPSPARPAR TQGPGRGCGH RTARPAASQQ DSM. It is sometimes possible for the material contained within the vial of "ITGB1BP3, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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